24 Results for "

Sulfate group

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "Sulfate group" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P86463
Synonyms: LHR antibody; BA-1 antibody; CD 44 antibody; CD44 antibody; CD44 antigen antibody; CD44 molecule; Indian blood group; antibody; CD44 molecule antibody; CD44_HUMAN antibody; CDw44 antibody; CDW44 antigen antibody; Cell surface glycoprotein CD44 antibody; chondroitin Sulfate proteoglycan 8 antibody; CSPG8 antibody; ECMR-III antibody; Epican antibody; Extracellular matrix receptor III antibody; GP90 lymphocyte homing/adhesion receptor antibody

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P80062
Synonyms: LHR antibody; BA-1 antibody; CD 44 antibody; CD44 antibody; CD44 antigen antibody; CD44 molecule (Indian blood group) antibody; CD44 molecule antibody; CD44_HUMAN antibody; CDw44 antibody; Cell surface glycoprotein CD44 antibody; chondroitin Sulfate proteoglycan 8 antibody; CSPG8 antibody; ECMR-III antibody; Epican antibody; Extracellular matrix receptor III antibody; GP90 lymphocyte homing/adhesion receptor antibody; HCELL antibody; hematopoietic cell E- and L-selectin ligand antibody; Heparan Sulfate proteoglycan antibody; Hermes antigen antibody; homing function and Indian blood group system antibody; HSA antibody; HUTCH-I antibody; HUTCH1 antibody; Hyaluronate receptor antibody; IN antibody; MC56 antibody; MDU2 antibody; MDU3 antibody

Host:  

Rabbit

Application:  

WB, IHC-P, FC

Reactivity:  

Human, Mouse

loading...
    loading...
Cat. No.: HY-121360
CAS No.: 143545-90-8
Cylindrospermopsin, a cyanotoxin, is a polycyclic uracil derivative containing guanidine and sulfate groups, which can inhibit protein synthesis and covalently modify DNA or RNA. Cylindrospermopsin induces hepatocellular hypertrophy, renal cellular hypertrophy, intracellular reactive oxygen species (ROS), DNA strand breaks, mitochondrial hyperpolarisation, ultrastructural damage, and altered gene expression in liver, kidney, and intestinal cells. Cylindrospermopsin can be used in research including hepatocellular carcinoma and water quality testing .
loading...
    loading...
Cat. No.: HY-157424
CAS No.: 102029-54-9
Purity:  80.00%
Synonyms: PAPS tetralithium salt
Research Areas:  

Metabolic Disease

3′-Phosphoadenosine 5′-phosphosulfate tetralithium salt (PAPS tetralithium salt) is the cosubstrate and the source of sulfonic acid groups in sulfation reactions. 3′-Phosphoadenosine 5′-phosphosulfate tetralithium salt is important for maintaining sulfation balance in living organisms .
loading...
    loading...
Cat. No.: HY-112624K
CAS No.: 9004-54-0
Synonyms: Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)
Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
loading...
    loading...
Cat. No.: HY-137855
CAS No.: 15220-11-8
Purity:  99.29%
4-Methylumbelliferyl sulfate (potassium), a fluorescent substrate, is commonly used to detect sulfatase activity in biochemical and biomedical research. It consists of a sulfate group attached to a fluorescent molecule, which can be cleaved by sulfatase enzymes. Upon cleavage, 4-Methylumbelliferyl sulfate releases a highly fluorescent product that can be detected using fluorescence microscopy or spectroscopy. The use of 4-Methylumbelliferyl sulfate as a substrate for sulfatase enzymes allows accurate detection and quantification of these enzymes in a variety of biological samples.
loading...
    loading...
Cat. No.: HY-164090
CAS No.: 482-67-7
Target:  

P2Y Receptor

Research Areas:  

Cardiovascular Disease

Adenosine 3'-phosphate 5'-phosphosulfate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
loading...
    loading...
Cat. No.: HY-E70186
CAS No.: 55354-43-3
Synonyms: EC:3.1.6.12; ARSB
Arylsulfatase B (EC:3.1.6.12, ARSB) removes a chemical group known as a sulfate from two GAGs called dermatan sulfate and chondroitin sulfate .
loading...
    loading...
Cat. No.: HY-W800787
CAS No.: 384847-49-8
Target:  

Liposome

Research Areas:  

Others

18:1 PE MCC is a reactive phospholipid containing a maleimide group. 18:1 PE MCC forms covalent bonds with thiol-modified chondroitin sulfate (CS) via thiol-maleimide reaction, and anchors CS to the surface of lipid membranes. 18:1 PE MCC is applicable to glycocalyx model construction and lipid membrane biophysics research .
loading...
    loading...
Cat. No.: HY-122350
CAS No.: 73245-91-7
Synonyms: SF-2052 Sulfate
Target:  

Antibiotic

Research Areas:  

Infection

Dactimicin sulfate (SF-2052 sulfate) is an antibiotic produced by Dactylosporangium matsuzakiense and belongs to the fortimicin antibiotic family. Dactimicin sulfate is an aminoglycoside antibiotic containing a carboximido group and inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria. Dactimicin sulfate can be used in research on infections caused by sensitive bacteria .
loading...
    loading...
Cat. No.: HY-115004
CAS No.: 1006604-91-6
Target:  

FAAH

Research Areas:  

Neurological Disease

MM-433593 is a potent and selective inhibitor of fatty acid amide hydrolase-1 (FAAH-1) that is orally administered to inhibit pain, inflammation, and related disorders. Pharmacokinetic studies of MM-433593 in macaques revealed a biphasic elimination profile with a rapid distribution phase and a slower elimination phase, with a systemic clearance of 8-11 mL/min/kg. MM-433593 exhibits moderate oral bioavailability (14-21%) and its metabolism primarily involves oxidation of the methyl group on the indole ring, resulting in a variety of sulfate, glucuronide, or glutathione-conjugated metabolites .
loading...
    loading...
Cat. No.: HY-107785R
CAS No.: 38899-05-7
Synonyms: D-Glucosamine-2-N-Sulfate sodium (Standard)
2-Deoxy-2-sulfoamino-D-glucose (sodium) (Standard) is the analytical standard of 2-Deoxy-2-sulfoamino-D-glucose (sodium). This product is intended for research and analytical applications. 2-Deoxy-2-sulfoamino-D-glucose sodium (D-Glucosamine-2-N-sulfate sodium) is an endogenous metabolite. The main regulatory mechanism of 2-Deoxy-2-sulfoamino-D-glucose sodium involves the interaction of sulfuric acid groups with biomolecules. Sulfate groups can influence the charge density and configuration of polysaccharides, thereby regulating their ability to bind to proteins such as antithrombin. This combination can enhance the activity of antithrombin, which in turn inhibits key enzymes in the blood clotting process to achieve anti-clotting effects. 2-Deoxy-2-sulfoamino-D-glucose sodium can be used to study the selective removal of n-sulfate groups from Heparin (HY-17567) which has important implications for understanding the biological activity of heparin and developing related drugs .
loading...
    loading...
Cat. No.: HY-E70606
Research Areas:  

Others

ATP sulfase, yeast is an ATP sulfatase. ATP sulfase, yeast catalyzes the activation of sulfate by transferring sulfate to the adenine monophosphate group of ATP to form adenosine-5'-phosphosulfate (APS) and pyrophosphate (PPi).
loading...
    loading...
Cat. No.: HY-187239A
Research Areas:  

Others

DSG-PEG2000-TAT is a functionalized PEGylated lipid conjugate composed of three modular components: distearoylglycerol (DSG) as the lipid anchoring group, PEG, and TAT peptide (YGRKKRRQRRR) (HY-P0281) as the terminal targeting/functional ligand. DSG-PEG2000-TAT can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against non-specific cell membrane penetration (heparan sulfate proteoglycans).
loading...
    loading...
Cat. No.: HY-187317
Research Areas:  

Others

DOPE-PEG1000-TAT is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, PEG, and TAT peptide (YGRKKRRQRRR) (HY-P0281) as the terminal targeting/functional ligand. DOPE-PEG1000-TAT can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against non-specific cell membrane penetration (heparan sulfate proteoglycans).
loading...
    loading...
Cat. No.: HY-187317A
Research Areas:  

Others

DOPE-PEG2000-TAT is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, PEG, and TAT peptide (YGRKKRRQRRR) (HY-P0281) as the terminal targeting/functional ligand. DOPE-PEG2000-TAT can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against non-specific cell membrane penetration (heparan sulfate proteoglycans).
loading...
    loading...
Cat. No.: HY-187317B
Research Areas:  

Others

DOPE-PEG3400-TAT is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, PEG, and TAT peptide (YGRKKRRQRRR) (HY-P0281) as the terminal targeting/functional ligand. DOPE-PEG3400-TAT can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against non-specific cell membrane penetration (heparan sulfate proteoglycans).
loading...
    loading...
Cat. No.: HY-187317C
Research Areas:  

Others

DOPE-PEG5000-TAT is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, PEG, and TAT peptide (YGRKKRRQRRR) (HY-P0281) as the terminal targeting/functional ligand. DOPE-PEG5000-TAT can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against non-specific cell membrane penetration (heparan sulfate proteoglycans).
loading...
    loading...
Cat. No.: HY-187327
Research Areas:  

Others

DMG-PEG1000-TAT is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, PEG, and TAT peptide (YGRKKRRQRRR) (HY-P0281) as the terminal targeting/functional ligand. DMG-PEG1000-TAT can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against non-specific cell membrane penetration (heparan sulfate proteoglycans).
loading...
    loading...
Cat. No.: HY-187327B
Research Areas:  

Others

DMG-PEG3400-TAT is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, PEG, and TAT peptide (YGRKKRRQRRR) (HY-P0281) as the terminal targeting/functional ligand. DMG-PEG3400-TAT can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against non-specific cell membrane penetration (heparan sulfate proteoglycans).
loading...
    loading...