1 Result for "

T133

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "T133" in MCE Product Catalog:

Cat. No.: HY-181650
CAS No.: 3101627-06-6
Research Areas:  

Cancer

T133 is an orally active ATP-competitive mTOR inhibitor with an IC50 of 0.34 nM and a Ki of 0.17 nM. T133 suppresses phosphorylation of AKT, S6K1, and 4EBP1. T133 inhibits cancer cell proliferation and migration, induces apoptosis, cell cycle arrest, and autophagy. T133 exhibits dose-dependent antitumor efficacy in xenograft mouse models. T133 can be used for the research of cancer, such as gastric cancer and lung cancer .
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