10 Results for "

TWEAK receptor

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "TWEAK receptor" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-122575
CAS No.: 4431-00-9
Purity:  ≥92.0%
Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs, with IC50s of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively . Aurintricarboxylic acid is a potent anti-influenza agent by directly inhibiting the neuraminidase . Aurintricarboxylic acid is an inhibitor of topoisomerase II and apoptosis . Aurintricarboxylic acid is a selective inhibitor of the TWEAK-Fn14 signaling pathway . Aurintricarboxylic acid also acts as a cystathionine-lyase (CSE) inhibitor with an IC50 of 0.6 μM . Aurintricarboxylic acid is a modifier of miRNAs that regulate miRNA function, with an IC50 of 0.47 µM .
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1
1 Cited Publications
Cat. No.: HY-P72434
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF12A; Tumor Necrosis Factor receptor Superfamily Member 12A; TNF receptor Superfamily Member 12A; FGF-Inducible 14; TWEAKR; TWEAK-receptor; FN14; Tumor Necrosis Factor receptor Superfamily, Member 12A; CD266; Type I Transmembrane Protein Fn14; Fibrob
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P99361
CAS No.: 1062149-33-0
Synonyms: PDL192; ABT-361; Anti-TNFRSF12A/TWEAKR/CD266 Reference Antibody (enavatuzumab)

Target:  

TNF Receptor

Research Areas:  

Cancer

Enavatuzumab (PDL192; ABT-361) is a humanized IgG1 monoclonal antibody targeting the receptor of TNF-like weak inducer of apoptosis (TWEAK). TWEAK (Fn14; TNFRSF12A), the natural ligand of the TWEAK receptor (TweakR), stimulates multiple cellular responses. Enavatuzumab induces tumor growth inhibition through direct TweakR signaling and antibody dependent cell-mediated cytotoxicity (ADCC). Enavatuzumab can actively recruits and activates myeloid effectors to kill tumor cells. Enavatuzumab inhibits the growth of various human TweakR-positive cancer cell lines and xenografts in vitro and in vivo .
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Cat. No.: HY-P992321

Target:  

TNF Receptor NF-κB STAT

Research Areas:  

Cancer

BAY-356, a potent TWEAK receptor agonist, is an aglycosylated anti-TWEAK receptor antibody. BAY-356 triggers TWEAKR hyperactivation, activates NFκB and STAT1 pathways, and undergoes TWEAKR-dependent internalization. BAY-356 can be used for the research of colorectal cancer, bladder cancer, non-small cell lung cancer and pancreatic cancer[1][2].
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Cat. No.: HY-P71909
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF12A; Tumor Necrosis Factor receptor Superfamily Member 12A; TNF receptor Superfamily Member 12A; FGF-Inducible 14; TWEAKR; TWEAK-receptor; FN14; Tumor Necrosis Factor receptor Superfamily, Member 12A; CD266; Type I Transmembrane Protein Fn14; Fibroblast Growth Factor-Inducible Immediate-Early Response Protein 14; CD266 Antigen
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P72435
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF12A; Tumor Necrosis Factor receptor Superfamily Member 12A; TNF receptor Superfamily Member 12A; FGF-Inducible 14; TWEAKR; TWEAK-receptor; FN14; Tumor Necrosis Factor receptor Superfamily, Member 12A; CD266; Type I Transmembrane Protein Fn14; Fibrob
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P72435A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF12A; Tumor Necrosis Factor receptor Superfamily Member 12A; TNF receptor Superfamily Member 12A; FGF-Inducible 14; TWEAKR; TWEAK-receptor; FN14; Tumor Necrosis Factor receptor Superfamily, Member 12A; CD266; Type I Transmembrane Protein Fn14; Fibroblast Growth Factor-Inducible Immediate-Early Response Protein 14; CD266 Antigen
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P82931
Synonyms: CD266 antigen; FGF inducible 14; Fibroblast growth factor inducible immediate early response protein 14; FN14; TNFRSF 12A; TWEAK receptor; TWEAKR

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P82931A
Synonyms: CD266 antigen; FGF inducible 14; Fibroblast growth factor inducible immediate early response protein 14; FN14; TNFRSF 12A; TWEAK receptor; TWEAKR

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P810450
Synonyms: FN14, TNFRSF 12A, TWEAK receptor, TWEAKR,

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IF-Tissue, IP

Reactivity:  

Human, Mouse, Rat

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