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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
UNC-51-like
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "UNC-51-like" in MCE Product Catalog:
42
42 Publications Verification
GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation .
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7 Cited Publications
LYN-1604 dihydrochloride is a potent UNC-51-like kinase 1 (ULK1) activator (EC50=18.94 nM) for the research of triple negative breast cancer (TNBC) .
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4 Cited Publications
Research Areas:
BL-918 is an orally active UNC-51-like kinase 1 (ULK1) activator with an EC50 of 24.14 nM. BL-918 exerts its cytoprotective autophagic effect by targeting ULK complex. BL-918 has the potential for Parkinson’s disease (PD) treatment .
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1 Cited Publications
Research Areas:
(Rac)-BL-918 is the racemate of BL-918. BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1), inducing cytoprotective autophagy for Parkinson’s disease treatment .
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Cat. No.: HY-101923A
CAS No.: 2216753-86-3
LYN-1604 hydrochloride is a potent UNC-51-like kinase 1 (ULK1) activator (EC50=18.94 nM) for the research of triple negative breast cancer (TNBC) .
Cat. No.: HY-P703314
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ULK3; UNC-51 like Kinase 3; Serine/Threonine-Protein Kinase ULK3; DKFZP434C131; FLJ90566; Non-Specific Serine/Threonine Protein Kinase; UNC-51-like Kinase 3 (C. Elegans); UNC-51-like Kinase 3
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-101923R
CAS No.: 2088939-99-3
Target:
Research Areas:
LYN-1604 (Standard) is the analytical standard of LYN-1604 (HY-101923). This product is intended for research and analytical applications. LYN-1604 is a potent UNC-51-like kinase 1 (ULK1) activator (EC50=18.94 nM) for the research of triple negative breast cancer (TNBC) .
Cat. No.: HY-101923BR
CAS No.: 2310109-38-5
Target:
Research Areas:
LYN-1604 dihydrochloride (Standard) is the analytical standard of LYN-1604 dihydrochloride (HY-101923B). This product is intended for research and analytical applications. LYN-1604 dihydrochloride is a potent UNC-51-like kinase 1 (ULK1) activator (EC50=18.94 nM) for the research of triple negative breast cancer (TNBC) .
Cat. No.: HY-P82610A
Synonyms: Serine/threonine-protein kinase ULK3; Ulk3; UNC 51 like kinase 3 (C. elegans); UNC-51-like kinase 3
Cat. No.: HY-10249R
CAS No.: 937174-76-0
Target:
Research Areas:
GSK-690693 (Standard) is the analytical standard of GSK-690693 (HY-10249). This product is intended for research and analytical applications. GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation .
Cat. No.: HY-E70875
ULK1 (unc-51 like autophagy activating kinase 1), one of the core human autophagy-related genes, encodes a serine-threonine kinase and the mammalian ortholog of the yeast ATG1 gene. ULK1 Recombinant Human Active Protein Kinase is a recombinant ULK1 protein that can be used to study ULK1-related functions .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
