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Cat. No.: HY-117413

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SR-17398

SR-17398 is an inhibitor for Unc-51-Like Kinase 1 (ULK1) with an IC₅₀ of 22.4 μM.

For research use only. We do not sell to patients.

CAS No.: 1496088-76-6
Formula: C₁₄H₁₈N₄O
Molecular Weight:258.32

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

SR-17398 Chemical Structure

CAS No.: 1496088-76-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

SR-17398 is an inhibitor for Unc-51-Like Kinase 1 (ULK1) with an IC₅₀ of 22.4 μM^[1].

IC₅₀ & Target

ULK1

22.4 μM (IC₅₀)

All ULK Isoforms :

ULK1
ULK2

Chemical Information

CAS No. 1496088-76-6
Molecular Weight 258.32
Formula C₁₄H₁₈N₄O
SMILES

O=C(C1CC(N)CCC1)NC2=CC3=C(NN=C3)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wood SD, et al., In Silico HTS and Structure Based Optimization of Indazole-Derived ULK1 Inhibitors. ACS Med Chem Lett. 2017 Nov 22;8(12):1258-1263. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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