23 Results for "

Urine metabolism

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "Urine metabolism" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W012722
CAS No.: 816-66-0
Synonyms: α-Ketoisocaproic acid
4-Methyl-2-oxopentanoic acid (α-Ketoisocaproic acid) is a metabolite of L-leucine and is involved in energy metabolism. 4-Methyl-2-oxopentanoic acid increases endoplasmic reticulum stress, promotes lipid accumulation in preadipocytes and insulin resistance by impairing mTOR and autophagy signaling pathways. 4-Methyl-2-oxopentanoic acid also causes oxidative damage, leading to cognitive deficits, inhibits α-ketoglutarate dehydrogenase activity, acts as an oxidative phosphorylation uncoupler and metabolic inhibitor. 4-Methyl-2-oxopentanoic acid acts as a nutrient signal and stimulates skeletal muscle protein synthesis. 4-Methyl-2-oxopentanoic acid can be used in the study of maple syrup urine disease .
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1
1 Cited Publications
Cat. No.: HY-128733
CAS No.: 122-79-2
Purity:  99.68%
Phenyl acetate is an endogenous metabolite and a metabolite of 2-phenylethylamine, which can be found in urine. Phenyl acetate regulates the metabolism of glutamine. In addition, Phenyl acetate can be used as a detection index for certain diseases, such as depression .
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Cat. No.: HY-113126
CAS No.: 2068-83-9
Purity:  ≥93.0%
3-Hydroxyisobutyric acid is an intermediate in the metabolic pathways of L-valine and thymine, and can be found in urine. 3-Hydroxyisobutyric acid is a secreted mediator of endothelial cell fatty acid transport and insulin resistance. 3-Hydroxyisobutyric acid can also inhibit key enzymes of energy metabolism in the cerebral cortex of young rats. The levels of 3-Hydroxyisobutyric acid are closely related to various diseases such as 3-hydroxyisobutyric aciduria, diabetes, and ketoacidosis .
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Cat. No.: HY-W561907
CAS No.: 85960-17-4
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

IMipenem and cilastatin sodium is a broad-spectrum Carbapenem Antibiotic combination. Imipenem (HY-B1369A) is a Carbapenem antibiotic. IMipenem demonstrates excellent activity against gram-positive and gram-negative aerobic and anaerobic organisms. Cilastatin (HY-A0166) is a renal Dehydropeptidase inhibitor that inhibits the metabolism of Imipenem by renal brush-border enzymes, thus increasing imipenem concentrations in urine .
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Cat. No.: HY-N9941
CAS No.: 30377-37-8
2,8-Dihydroxyadenine is an endogenous metabolite that forms crystals in urine, leading to kidney stone formation and crystal deposition in the kidney. 2,8-Dihydroxyadenine induces crystal-induced tubular injury, inflammation, and fibrosis through crystal deposition in renal tubules, where crystals are excreted in urine, internalized by tubular epithelial cells, and transported to the interstitium. 2,8-Dihydroxyadenine upregulates CD44 expression near crystals, TNF-α signaling through NF-κB, and mTORC1 signaling, while inducing actin stress fiber formation and cytoskeletal remodeling. 2,8-Dihydroxyadenine downregulates epithelial-mesenchymal transition pathways and oxidative phosphorylation, and induces changes affecting inflammation, metabolism, and cell cycle regulation. 2,8-Dihydroxyadenine can be used in research on kidney disease, adenine phosphoribosyltransferase deficiency, and kidney stone disease .
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Cat. No.: HY-128733R
CAS No.: 122-79-2
Phenyl acetate (Standard) is the analytical standard of Phenyl acetate. This product is intended for research and analytical applications. Phenyl acetate is an endogenous metabolite and a metabolite of 2-phenylethylamine, which can be found in urine. Phenyl acetate regulates the metabolism of glutamine. In addition, Phenyl acetate can be used as a detection index for certain diseases, such as depression.
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Cat. No.: HY-W012168
CAS No.: 1205-30-7
Target:  

Carbonic Anhydrase

Research Areas:  

Metabolic Disease

4-Chloro-3-sulfamoylbenzoic acid is a weak inhibitor of human carbonic anhydrase isoforms hCA I, hCA II, hCA IV, and hCA IX, and a synthesis intermediate for carbonic anhydrase inhibitors. 4-Chloro-3-sulfamoylbenzoic acid is the major metabolite of tripamide detected in tissues, urine, and feces of rats and rabbits following Tripamide (HY-106570) administration. 4-Chloro-3-sulfamoylbenzoic acid can be used for the study of carbonic anhydrase inhibition and species differences in drug metabolism .
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Cat. No.: HY-W002110
CAS No.: 1131-94-8
Synonyms: 3-Hydroxy-4-methoxyphenylacetic acid; iso-HVA; Homoisovanillic acid
Isohomovanillic acid (3-Hydroxy-4-methoxyphenylacetic acid) is a product of catecholamine metabolism. Isohomovanillic acid can be isolated from urine. Isohomovanillic acid can be used in the research of Parkinson's disease .
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Cat. No.: HY-126121
CAS No.: 51146-55-5
Synonyms: (±)-2-Hydroxy Ibuprofen
2-Hydroxy Ibuprofen ((±)-2-Hydroxy Ibuprofen) is a major oxidative metabolite of Ibuprofen (HY-78131) . 2-Hydroxy Ibuprofen undergoes phase II metabolism, forming a β-1-O-acyl glucuronide conjugate at the carboxyl group of its propionic acid side chain. 2-Hydroxy Ibuprofen can be used for metabolism-related research .
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Cat. No.: HY-113104
CAS No.: 1852-43-3
Synonyms: ADT-G
Research Areas:  

Metabolic Disease

Androsterone glucuronide (ADT-G) is one of the main metabolites of oral testosterone in humans and can be found in urine. The level of Androsterone glucuronide can reflect the absorption and hepatic metabolism of testosterone .
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Cat. No.: HY-128733S
CAS No.: 22705-26-6
Phenyl acetate-d5 is the deuterium labeled Phenyl acetate. Phenyl acetate is an endogenous metabolite and a metabolite of 2-phenylethylamine, which can be found in urine. Phenyl acetate regulates the metabolism of glutamine. In addition, Phenyl acetate can be used as a detection index for certain diseases, such as depression .
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Cat. No.: HY-160542
CAS No.: 37162-93-9
Target:  

Endogenous Metabolite

Research Areas:  

Others

Clenhexyl hydrochloride is a urinary metabolite useful for quantitative screening in doping control screening programs .
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Cat. No.: HY-156558
CAS No.: 1365541-49-6
SeGalNac is a selenium metabolite found in human urine. SeGalNac can be used in the study of selenoglucose metabolism .
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Cat. No.: HY-W002110R
CAS No.: 1131-94-8
Synonyms: 3-Hydroxy-4-methoxyphenylacetic acid (Standard); iso-HVA (Standard); Homoisovanillic acid (Standard)
Isohomovanillic acid (Standard) is an analytical standard of Isohomovanillic acid (HY-W002110). This product is intended for research and analytical applications. Isohomovanillic acid (3-Hydroxy-4-methoxyphenylacetic acid) is a product of catecholamine metabolism. Isohomovanillic acid can be isolated from urine. Isohomovanillic acid can be used in the research of Parkinson's disease .
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Cat. No.: HY-N15717
CAS No.: 321365-68-8
(erythro) 1′,2′-Dihydroxyasarone is a metabolite of Beta-asarone (HY-N1501) and can also be isolated from the roots of Acorus tatarinowii. (erythro) 1′,2′-Dihydroxyasarone can form glucuronic acid conjugates in vivo and be excreted in urine. (erythro) 1′,2′-Dihydroxyasarone can serve as a marker for the metabolism and toxic risk assessment of Beta-asarone .
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Cat. No.: HY-114598
CAS No.: 152595-59-0
Target:  

SGLT

Research Areas:  

Metabolic Disease

WAY-123783 is a potent, selective and orally active sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor producing activity after metabolism. WAY-123783 can increase the excretion of sugar in urine and at the same time lower the blood sugar level in db/db mice (ED50 = 9.85 mg/kg). WAY-123783 can be used for the research of metabolic disease, such as diabetes .
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Cat. No.: HY-113126A
CAS No.: 1219589-99-7
3-Hydroxyisobutyric acid sodium is an intermediate in the metabolic pathways of L-valine and thymine, and can be found in urine. 3-Hydroxyisobutyric acid sodium is a secreted mediator of endothelial cell fatty acid transport and insulin resistance. 3-Hydroxyisobutyric acid sodium can also inhibit key enzymes of energy metabolism in the cerebral cortex of young rats. The levels of 3-Hydroxyisobutyric acid sodium are closely related to various diseases such as 3-hydroxyisobutyric aciduria, diabetes, and ketoacidosis .
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Cat. No.: HY-145534
CAS No.: 152064-94-3
Synonyms: CAR 8:1; C8:1 Carnitine; L-Carnitine trans-2-octenoyl ester
Research Areas:  

Metabolic Disease

trans-2-Octenoyl-L-carnitine (CAR 8:1; C8:1 Carnitine; L-Carnitine trans-2-octenoyl ester) is a medium-chain monounsaturated acylcarnitine that rarely occurs in healthy humans, and it is a fatty acid oxidation-related metabolite associated with gut microbiota-host co-metabolism. trans-2-Octenoyl-L-carnitine can serve as an analytical reference standard for qualitative and quantitative detection of carnitine metabolites in scientific research, particularly in human urine samples.
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Cat. No.: HY-126121R
CAS No.: 51146-55-5
Synonyms: (±)-2-Hydroxy Ibuprofen (Standard)
2-Hydroxy Ibuprofen (Standard) ((±)-2-Hydroxy Ibuprofen (Standard)) is the analytical standard of 2-Hydroxy Ibuprofen (HY-126121). This product is intended for research and analytical applications. 2-Hydroxy Ibuprofen ((±)-2-Hydroxy Ibuprofen) is a major oxidative metabolite of Ibuprofen (HY-78131) . 2-Hydroxy Ibuprofen undergoes phase II metabolism, forming a β-1-O-acyl glucuronide conjugate at the carboxyl group of its propionic acid side chain. 2-Hydroxy Ibuprofen can be used for metabolism-related research .
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Cat. No.: HY-126121S
CAS No.: 1217055-71-4
Synonyms: (±)-2-Hydroxy Ibuprofen-d6
2-Hydroxy Ibuprofen-d6 ((±)-2-Hydroxy Ibuprofen-d6)is the deuterated-labeled 2-Hydroxy Ibuprofen (HY-126121). 2-Hydroxy Ibuprofen is a major oxidative metabolite of Ibuprofen (HY-78131) . 2-Hydroxy Ibuprofen undergoes phase II metabolism, forming a β-1-O-acyl glucuronide conjugate at the carboxyl group of its propionic acid side chain. 2-Hydroxy Ibuprofen can be used for metabolism-related research .
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