1205-30-7
Chemical Structure
4-Chloro-3-sulfamoylbenzoic acid
- CAS No.: 1205-30-7
- Formula:C7H6ClNO4S
- Molecular Weight:235.64
IUPAC Name: 4-chloro-3-sulfamoylbenzoic acid
InChIKey: FHQAWINGVCDTTG-UHFFFAOYSA-N
SMILES: ClC1=C(S(N)(=O)=O)C=C(C(O)=O)C=C1
Biological Activity: 4-Chloro-3-sulfamoylbenzoic acid is a weak inhibitor of human carbonic anhydrase isoforms hCA I, hCA II, hCA IV, and hCA IX, and a synthesis intermediate for carbonic anhydrase inhibitors. 4-Chloro-3-sulfamoylbenzoic acid is the major metabolite of tripamide detected in tissues, urine, and feces of rats and rabbits following Tripamide (HY-106570) administration. 4-Chloro-3-sulfamoylbenzoic acid can be used for the study of carbonic anhydrase inhibition and species differences in drug metabolism[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-Chloro-3-sulfamoylbenzoic acid | 99.85% | 4-Chloro-3-sulfamoylbenzoic acid is a weak inhibitor of human carbonic anhydrase isoforms hCA I, hCA II, hCA IV, and hCA IX, and a synthesis intermediate for carbonic anhydrase inhibitors. 4-Chloro-3-sulfamoylbenzoic acid is the major metabolite of tripamide detected in tissues, urine, and feces of rats and rabbits following Tripamide (HY-106570) administration. 4-Chloro-3-sulfamoylbenzoic acid can be used for the study of carbonic anhydrase inhibition and species differences in drug metabolism. | ||||||||||||||||||||
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- [1]. Swain B, et al. Synthesis of a new series of 3-functionalised-1-phenyl-1,2,3-triazole sulfamoylbenzamides as carbonic anhydrase I, II, IV and IX inhibitors. J Enzyme Inhib Med Chem. 2019;34(1):1199-1209. [Content Brief]
- [2]. Horie T, et al. Studies on metabolism of tripamide. III. Metabolic fate of 14C-tripamide in rats and rabbits. Jpn J Pharmacol. 1982;32(6):1041-1049. [Content Brief]
Keywords
