IMipenem and cilastatin sodium
Based on 1 Customer Validation
IMipenem and cilastatin sodium is a broad-spectrum Carbapenem Antibiotic combination. Imipenem (HY-B1369A) is a Carbapenem antibiotic. IMipenem demonstrates excellent activity against gram-positive and gram-negative aerobic and anaerobic organisms. Cilastatin (HY-A0166) is a renal Dehydropeptidase inhibitor that inhibits the metabolism of Imipenem by renal brush-border enzymes, thus increasing imipenem concentrations in urine.
For research use only. We do not sell to patients.
- Purity: 98.86%
- CAS No.: 85960-17-4
- Formula: C28H42N5NaO9S2
- Molecular Weight:679.78
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Antibiotic Isoforms
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 85960-17-4
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Appearance Solid
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Molecular Weight 679.78
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Formula C28H42N5NaO9S2
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Color Off-white to light yellow
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SMILES
C[C@@H](O)[C@@H]1[C@H]2CC(SCCNC=N)=C(C(O)=O)N2C1=O.CC3(C)C[C@@H]3C(N/C(C([O-])=O)=C\CCCCSC[C@H](N)C(O)=O)=O.[Na+]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 20 mg/mL (29.42 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.4711 mL | 7.3553 mL | 14.7106 mL | 36.7766 mL |
| 5 mM | 0.2942 mL | 1.4711 mL | 2.9421 mL | 7.3553 mL | |
| 10 mM | 0.1471 mL | 0.7355 mL | 1.4711 mL | 3.6777 mL | |
| 15 mM | 0.0981 mL | 0.4904 mL | 0.9807 mL | 2.4518 mL | |
| 20 mM | 0.0736 mL | 0.3678 mL | 0.7355 mL | 1.8388 mL | |
| 25 mM | 0.0588 mL | 0.2942 mL | 0.5884 mL | 1.4711 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
- IMipenem and cilastatin
- 85960-17-4
- Antibiotic
- Bacterial
- pelvic infections
- renal dehydropeptidase inhibitor
- gram-positive anaerobic organisms
- intra-abdominal infections
- gram-negative aerobic organisms
- renal brush-border enzymes
- gram-negative anaerobic organisms
- Pseudomonas aeruginosa
- antimicrobial agent
- gram-positive aerobic organisms
- Inhibitor
- inhibitor
- inhibit