1 Result for "

VCU1012

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VCU1012" in MCE Product Catalog:

Cat. No.: HY-187560
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

VCU-1012 is a serotonin 2A receptor (5-HT2AR) agonist, with a pEC50 of 5.81 and a pKi of 5.75 against human receptors. VCU-1012 binds to the canonical orthosteric binding pocket of 5-HT2AR, triggers intracellular calcium release and Gαq protein dissociation, and its agonistic activity depends on specific amino acid residues in the receptor binding pocket. VCU-1012 can be used in research related to depression, anxiety disorders, and chemotherapy-induced mood disorders .
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