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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
VE-cadherin
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "VE-cadherin" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-125864B
CAS No.: 9001-32-5
Research Areas:
Murine Fibrinogen is a native fibrinogen derived from mouse plasma. Murine Fibrinogen acts as a cerebrovascular permeability enhancer. Murine Fibrinogen activates matrix metalloproteinase-9 (MMP-9), downregulates the expression of vascular endothelial cadherin (VE-cadherin), and upregulates the expression of plasmalemmal vesicle-associated protein-1 (PV-1). Murine Fibrinogen increases macromolecular leakage from pial veins, thereby disrupting the microvascular integrity of cerebral blood vessels. Murine Fibrinogen can be used in studies related to cerebrovascular dysfunction .
2
2 Cited Publications
Cat. No.: HY-P81097
Synonyms: VE-cadherin; 7B4 antigen; VECD; Vascular endothelial cell cadherin; 7B 4; 7B4; 7B4 antigen; cadherin 5; cadherin 5 type 2; cadherin-5; cadherin5; CD 144; CD144 antigen; CDH 5; CDH5; CDH5 protein; Vascular endothelial cadherin; VE Cad antibody VEC; CADH5_HUMAN.
Target:
Synonyms: Fibrin-deriVEd peptide Bβ15-42
Target:
Research Areas:
Cat. No.: HY-P10580
CAS No.: 1359657-45-6
Research Areas:
Cat. No.: HY-124314
CAS No.: 1620582-23-1
Research Areas:
LEI-106 is a dual ABHD6 and DAGL-α inhibitor, with a Ki of 0.8 μM for ABHD6, and an IC50 of 18 nM and a Ki of 0.7 μM for DAGL-α. LEI-106 blocks the synthesis of 2-arachidonoylglycerol, reduces the level of endothelial cell-derived 2-arachidonoylglycerol, without altering the levels of cannabinoids and diacylglycerol. LEI-106 is applicable to research related to diet-induced obesity and metabolic syndrome .
Cat. No.: HY-P10580A
Research Areas:
Cat. No.: HY-P73557
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDH5; cadherin 5, Type 2, VE-cadherin (Vascular Epithelium); cadherin 5; cadherin 5, Type 2 (Vascular Endothelium); Vascular Endothelial cadherin; 7B4 Antigen; VE-cadherin; CDNA FLJ51088, Highly Similar To cadherin-5; cadherin-5; Endothelial-Specific Cadh
Species:
Rat
Source:
HEK293
Cat. No.: HY-P73559
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDH5; cadherin 5, Type 2, VE-cadherin (Vascular Epithelium); cadherin 5; cadherin 5, Type 2 (Vascular Endothelium); Vascular Endothelial cadherin; 7B4 Antigen; VE-cadherin; CDNA FLJ51088, Highly Similar To cadherin-5; cadherin-5; Endothelial-Specific Cadh
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P73560A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDH5; cadherin 5, Type 2, VE-cadherin (Vascular Epithelium); cadherin 5; cadherin 5, Type 2 (Vascular Endothelium); Vascular Endothelial cadherin; 7B4 Antigen; VE-cadherin; CDNA FLJ51088, Highly Similar To cadherin-5; cadherin-5; Endothelial-Specific Cadh
Species:
Human
Source:
HEK293
Cat. No.: HY-183377
CAS No.: 1260071-76-8
Target:
EGFR Akt MMP HIF/HIF Prolyl-Hydroxylase mTOR VEGFR NF-κB Reactive Oxygen Species (ROS) Cadherin
Research Areas:
DMBT is an orally effective anti-tumor metastasis and anti-angiogenesis agent. DMBT downregulates key molecules such as EGFR/p-Akt/HIF-1α/VEGF/MMP-9, inhibits the HIF-1α/VE-cadherin (cadherin)/MMPs and Nrf2/HO-1 signaling pathways, and reduces hypoxia-induced ROS levels as well as the secretion and activity of MMP-9. DMBT inhibits hypoxia-induced vasculogenic mimicry, cancer cell migration, invasion and metastasis, and exhibits no obvious cytotoxicity to normal cells. DMBT reduces the area of laser-induced choroidal neovascularization lesions. DMBT can be used in studies related to breast cancer, melanoma and macular degeneration .
Cat. No.: HY-NP216
Synonyms: LecB
Cat. No.: HY-184654
CAS No.: 2169267-60-9
Target:
Synaptic Vesicle Proteins NF-κB ERK Akt HIF/HIF Prolyl-Hydroxylase Interleukin Related MyD88 TNF Receptor Caspase Formyl Peptide Receptor (FPR)
Research Areas:
MR-39 is a FPR2 agonist (EC50 = 3.9 μM). MR-39 activates FPR2 to promote neuroinflammation resolution (downregulates IL-1β and TNF-α, modulates NF-κB), upregulates synaptic proteins (synaptic proteins) and improves dendritic spine morphology. MR-39 inhibits MAPK/ERK and AKT phosphorylation in glioblastoma, induces S-phase arrest, and suppresses migration, angiogenesis, and hypoxic adaptation. MR-39 reduces Aβ plaque burden via inhibiting MyD88/NF-κB and NLRP3 inflammasome. MR-39 can be used for research on autism spectrum disorder, Alzheimer's disease, and glioblastoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
