88650-17-3
Chemical Structure
FX-06
Synonym(s): Fibrin-derived peptide Bβ15-42
- CAS No.: 88650-17-3
- Formula:C133H216N44O38
- Molecular Weight:3039.41
SMILES: C(=O)(N1[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(NCC(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)=O)=O)=O)=O)CO)=O)[C@H](CC)C)=O)CCC2)CCC1)[C@H]4N(C([C@@H](NC(=O)[C@H]5N(C([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]6N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]7N(C([C@@H](NC([C@H](CC8=CN=CN8)NC(CN)=O)=O)CCCNC(=N)N)=O)CCC7)CC(C)C)=O)CC(O)=O)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCC(O)=O)=O)CCC(O)=O)=O)C)=O)CCC6)CO)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCC5)C)=O)CCC4
Biological Activity: FX-06 (Fibrin-derived peptide Bβ15-42) is a fibrin Bbeta chain-derived peptide. FX-06 binds to VE-cadherin and inhibits leukocyte transmigration and initiates VE-cadherin-mediated signaling. FX-06 can be used in the research of ischemia/reperfusion injury, Dengue shock syndrome (DSS)[1][2][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FX-06 | 99.73% | FX-06 (Fibrin-derived peptide Bβ15-42) is a fibrin Bbeta chain-derived peptide. FX-06 binds to VE-cadherin and inhibits leukocyte transmigration and initiates VE-cadherin-mediated signaling. FX-06 can be used in the research of ischemia/reperfusion injury, Dengue shock syndrome (DSS). | ||||||||||||||||||||
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- [1]. Ahrens I, et al. FX-06, a fibrin-derived Bbeta15-42 peptide for the potential treatment of reperfusion injury following myocardial infarction. Curr Opin Investig Drugs. 2009 Sep;10(9):997-1003. [Content Brief]
- [2]. Zou F, et al. Identification of novel allosteric inhibitors of mutant isocitrate dehydrogenase 1 by cross docking-based virtual screening. Bioorg Med Chem Lett. 2018 Feb 1;28(3):388-393. [Content Brief]
- [4]. Gröger M, et al. Peptide Bbeta(15-42) preserves endothelial barrier function in shock. PLoS One. 2009;4(4):e5391. [Content Brief]
Keywords