Vibrio cholerae

By Targets:	Antibiotic (1) Bacterial (7) Biochemical Assay Reagents (1) DNA/RNA Synthesis (2) Drug Derivative (1) Endogenous Metabolite (1) Environmental Pollutants (1) Fluorescent Dye (2) HCV (1) Influenza Virus (1) Insecticide (1) nAChR (1) Reactive Oxygen Species (ROS) (1)
By Research Areas:	Infection (8) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (1)

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-P3394

**Cholera toxin B subunit, from vibrio cholerae** CTB, from Vibrio cholerae	Biochemical Assay Reagents	Others
Cholera toxin B subunit, from vibrio cholerae (CTB, from vibrio cholerae) is non-toxic to cells and possesses no intrinsic adenylate cyclase activity. Cholera toxin B subunit, from vibrio cholerae attaches to cells by binding to ganglioside GM1.8 CTB has been shown to be a good label for microglial cells (due to the enrichment of ganglioside GM1 on their cell surface), but not for oligodendrocytes or astrocytes. Cholera toxin B subunit, from vibrio cholerae has been reported to be an excellent tracer for the study of axonal transport using immunohistochemical methods. Cholera toxin B subunit, from vibrio cholerae has been widely used as a marker of membrane lipid rafts .

HY-P1934

Cyclo(Phe-Pro) 5+ Cited Publications Cyclo(phenylalanylprolyl); A-64863	HCV Bacterial Antibiotic Reactive Oxygen Species (ROS)	Infection
Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) is a quorum-sensing molecule of Vibrio vulnificus that specifically interacts with RIG-I, inhibiting RIG-I polyubiquitination, suppressing IRF-3 activation, and reducing type I interferon production. Cyclo(Phe-Pro) enhances susceptibility to HCV and influenza virus and also alleviates plant aluminum toxicity stress. The mechanism of Cyclo(Phe-Pro) involves the regulation of host immune signaling pathways, bacterial virulence gene expression, and plant antioxidant systems, making it a promising candidate for research in viral infections, bacterial virulence regulation, and agricultural stress resistance .

HY-D2381

AF 488 maleimide	Fluorescent Dye	Others
AF 488 maleimide is a thiol-reactive dye used to label SH groups of proteins, which can attach the AF 488 fluorophore to cysteine residue-containing proteins and peptides as well as other thiolated molecules. AF 488 maleimide enables real-time visualization of dynamic pilus extension and retraction in live bacterial cells via epifluorescence microscopy (Ex/Em = 470/520 nm) .

HY-D1191

SYBR green I chloride 3 Publications Verification	Fluorescent Dye DNA/RNA Synthesis	Others
SYBR Green I chloride is a highly sensitive fluorescent nucleic acid dye that binds specifically to the minor groove of double-stranded DNA or intercalates between base pairs. SYBR Green I chloride exhibits weak fluorescence in the unbound state but emits bright fluorescence upon binding, and it preferentially binds to large-fragment DNA and DNA with high G+C content. SYBR Green I chloride is suitable for real-time PCR technology; its fluorescence intensity correlates with the amount and size of amplification products, enabling accurate quantification of gene expression and discrimination of amplicons via melting curve analysis without additional post-processing. SYBR Green I chloride is widely used in preclinical in vitro nucleic acid detection .

HY-135783

AT 1001 1 Publications Verification	nAChR	Neurological Disease Metabolic Disease Inflammation/Immunology
AT 1001 is an orally effective α3β4 nicotinic acetylcholine receptor (α3β4 nAChR) antagonist with a K_i value of 2.64 nM. AT 1001 reversibly blocks Epibatidine (HY-101078)-induced inward currents in HEK cells transfected with α3β4 nAChR. AT 1001 dose-dependently blocks nicotine self-administration behavior in rats, alleviates gluten-induced gastrointestinal symptoms, blocks tight junction toxin-induced immune responses, and reduces the incidence of type 1 diabetes in rats. AT 1001 can be used in the research of nicotine addiction and celiac disease .

HY-145376

Cholera autoinducer 1 CAI-1	Bacterial	Others
Cholera autoinducer 1 is Vibrio cholerae autoinducer (S)-3-hydroxytridecan-4-one. Cholera autoinducer 1 influences chemotaxis in C. elegans .

HY-115846

ML370	Bacterial	Infection
ML370 is an antibacterial agent. ML370 exerts antibacterial activity by inhibiting the activity of Vibrio cholerae LuxO kinase. ML370 can be used in the research of infectious diseases such as cholera .

HY-P2988H

Neuraminidase,Vibrio cholerae	Influenza Virus	Infection
Neuraminidase,Vibrio cholerae (EC 3.2.1.18) is a glycoside hydrolase enzyme that cleave the glycosidic linkages of neuraminic acids.

HY-123504

ML344	Bacterial	Infection
ML344 is an agonist of Vibrio cholerae CqsS, a transmembrane receptor .

HY-115845

ML366	DNA/RNA Synthesis Endogenous Metabolite	Infection
ML366 is an inhibitor of Vibrio cholerae Quorum Sensing, exhibiting activity by targeting the LuxO response regulator.

HY-N14433

Fumigatin	Bacterial	Infection
Fumigatin has anti-Gram-positive bacteria, negative bacteria (weak) and vibrio cholerae activities .

HY-N19291

Perosamine D-Perosamine	Drug Derivative	Others
Perosamine is a dideoxysugar that can be isolated from the O-antigens of Gram-negative bacteria, including Vibrio cholerae O1 and Escherichia coli O157:H7 .

HY-B2180

Dichloroisocyanurate sodium	Environmental Pollutants Bacterial Insecticide	Infection
Dichloroisocyanurate sodium is a synthetic organochlorine compound belonging to triazine derivatives, and is commonly used as a disinfectant and biocide. Dichloroisocyanurate sodium can release hypochlorous acid to inactivate waterborne bacteria, viruses, helminths and protozoa, and can act as a hypochlorous acid reservoir to provide sustained biocidal protection .

HY-N13274

Dotriacontanoic acid Lacceroic acid	Bacterial	Infection
Dotriacontanoic acid (Lacceroic acid) is a fatty acid found in Limnophila polystachya Benth. Dotriacontanoic acid exhibits anti-bacterial activity against multiple gram-negative bacteria .

Cat. No.	Nombre del producto	Type

HY-D2381

AF 488 maleimide	Fluorescent Dyes
AF 488 maleimide is a thiol-reactive dye used to label SH groups of proteins, which can attach the AF 488 fluorophore to cysteine residue-containing proteins and peptides as well as other thiolated molecules. AF 488 maleimide enables real-time visualization of dynamic pilus extension and retraction in live bacterial cells via epifluorescence microscopy (Ex/Em = 470/520 nm) .

HY-D1191

SYBR green I chloride 3 Publications Verification	Fluorescent Dyes
SYBR Green I chloride is a highly sensitive fluorescent nucleic acid dye that binds specifically to the minor groove of double-stranded DNA or intercalates between base pairs. SYBR Green I chloride exhibits weak fluorescence in the unbound state but emits bright fluorescence upon binding, and it preferentially binds to large-fragment DNA and DNA with high G+C content. SYBR Green I chloride is suitable for real-time PCR technology; its fluorescence intensity correlates with the amount and size of amplification products, enabling accurate quantification of gene expression and discrimination of amplicons via melting curve analysis without additional post-processing. SYBR Green I chloride is widely used in preclinical in vitro nucleic acid detection .

SYBR green I chloride

3 Publications Verification

Fluorescent Dyes

SYBR Green I chloride is a highly sensitive fluorescent nucleic acid dye that binds specifically to the minor groove of double-stranded DNA or intercalates between base pairs. SYBR Green I chloride exhibits weak fluorescence in the unbound state but emits bright fluorescence upon binding, and it preferentially binds to large-fragment DNA and DNA with high G+C content. SYBR Green I chloride is suitable for real-time PCR technology; its fluorescence intensity correlates with the amount and size of amplification products, enabling accurate quantification of gene expression and discrimination of amplicons via melting curve analysis without additional post-processing. SYBR Green I chloride is widely used in preclinical in vitro nucleic acid detection .

Cat. No.	Nombre del producto	Type

HY-P3394

**Cholera toxin B subunit, from vibrio cholerae** CTB, from Vibrio cholerae	Biochemical Assay Reagents
Cholera toxin B subunit, from vibrio cholerae (CTB, from vibrio cholerae) is non-toxic to cells and possesses no intrinsic adenylate cyclase activity. Cholera toxin B subunit, from vibrio cholerae attaches to cells by binding to ganglioside GM1.8 CTB has been shown to be a good label for microglial cells (due to the enrichment of ganglioside GM1 on their cell surface), but not for oligodendrocytes or astrocytes. Cholera toxin B subunit, from vibrio cholerae has been reported to be an excellent tracer for the study of axonal transport using immunohistochemical methods. Cholera toxin B subunit, from vibrio cholerae has been widely used as a marker of membrane lipid rafts .

Cholera toxin B subunit, from vibrio cholerae

CTB, from Vibrio cholerae

Biochemical Assay Reagents

Cholera toxin B subunit, from vibrio cholerae (CTB, from vibrio cholerae) is non-toxic to cells and possesses no intrinsic adenylate cyclase activity. Cholera toxin B subunit, from vibrio cholerae attaches to cells by binding to ganglioside GM1.8 CTB has been shown to be a good label for microglial cells (due to the enrichment of ganglioside GM1 on their cell surface), but not for oligodendrocytes or astrocytes. Cholera toxin B subunit, from vibrio cholerae has been reported to be an excellent tracer for the study of axonal transport using immunohistochemical methods. Cholera toxin B subunit, from vibrio cholerae has been widely used as a marker of membrane lipid rafts .

Cat. No.	Nombre del producto	Target	Research Area

HY-P1934

Cyclo(Phe-Pro) 5+ Cited Publications Cyclo(phenylalanylprolyl); A-64863	HCV Bacterial Antibiotic Reactive Oxygen Species (ROS)	Infection
Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) is a quorum-sensing molecule of Vibrio vulnificus that specifically interacts with RIG-I, inhibiting RIG-I polyubiquitination, suppressing IRF-3 activation, and reducing type I interferon production. Cyclo(Phe-Pro) enhances susceptibility to HCV and influenza virus and also alleviates plant aluminum toxicity stress. The mechanism of Cyclo(Phe-Pro) involves the regulation of host immune signaling pathways, bacterial virulence gene expression, and plant antioxidant systems, making it a promising candidate for research in viral infections, bacterial virulence regulation, and agricultural stress resistance .

Cat. No.	Nombre del producto	Category	Target	Chemical Structure

HY-N14433

Fumigatin	Quinones Microorganisms Benzene Quinones Source Classification	Bacterial
Fumigatin has anti-Gram-positive bacteria, negative bacteria (weak) and vibrio cholerae activities .

HY-N19291

Perosamine D-Perosamine	Structural Classification Productos naturales Microorganisms Source Classification	Drug Derivative
Perosamine is a dideoxysugar that can be isolated from the O-antigens of Gram-negative bacteria, including Vibrio cholerae O1 and Escherichia coli O157:H7 .

HY-N13274

Dotriacontanoic acid Lacceroic acid	Structural Classification Ketones, Aldehydes, Acids Marine natural products Source Classification	Bacterial
Dotriacontanoic acid (Lacceroic acid) is a fatty acid found in Limnophila polystachya Benth. Dotriacontanoic acid exhibits anti-bacterial activity against multiple gram-negative bacteria .

Cat. No.	Compare	Nombre del producto	Species	Source	Image

HY-P704223

	Vibrio cholerae serotype O1 CTXB Protein (HEK293, His) Cholera enterotoxin subunit B/CTxB (Vibrio cholerae); L(strain ATCC 39315 / El Tor Inaba N16961	Virus	HEK293
	The pentameric ring of the B subunit of the CTXB protein guides the A subunit by binding to GM1 ganglioside on intestinal epithelial cells. This loop binds five GM1 gangliosides and promotes the specific interaction of the toxin with its cellular receptor. Vibrio cholerae serotype O1 CTXB Protein (HEK293, His) is the recombinant virus-derived Vibrio cholerae serotype O1 CTXB protein, expressed by HEK293, with C-His labeled tag.

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