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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
adipogenic activity
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "adipogenic activity" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-N4103
CAS No.: 17605-67-3
Category:
other families Metabolic Disease Plants Endogenous metabolite Disease Research Fields Steroids
Target:
2
2 Cited Publications
Cat. No.: HY-N0526
CAS No.: 53209-27-1
1
1 Cited Publications
Cat. No.: HY-N0704
CAS No.: 55576-66-4
1
1 Cited Publications
Synonyms: (-)-Eudesmin; Eudesmine; (-)-Eudesmine
Category:
Infection Magnoliaceae Lignans Metabolic Disease Magnolia Liliflora Desr. Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology
Target:
1
1 Cited Publications
Cat. No.: HY-N3027
CAS No.: 117230-33-8
Category:
Triterpenes Leguminosae Glycine max (L.) merr Terpenoids Metabolic Disease Plants Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-N4253
CAS No.: 173792-61-5
Synonyms: N-FMOC-leucine; NPC 15199; NSC 334290
Target:
Research Areas:
Fmoc-Leucine (N-FMOC-leucine) is an anti-inflammatory agent that not only promotes extracellular Ca 2+ influx but also facilitates intracellular Ca 2+ release. Fmoc-Leucine is a selective ligand for PPARγ (Ki = 15 μM), exhibiting insulin-sensitizing effects but with weak fatogenic activity. Fmoc-Leucine exhibits unique self-assembly properties and can form transient gels, stable gels, or crystals/2D sheets through different pathways. Fmoc-Leucine can be used in the research of diabetes, colitis, and bladder cancer .
Cat. No.: HY-N1984
CAS No.: 80286-58-4
Synonyms: Qing Hao acid; Artemisinic acid; Arteannuic acid
Category:
Infection Terpenoids Sesquiterpenes Artemisia carvifolia Buch.-Ham. ex Roxb. Metabolic Disease Plants Compositae Disease Research Fields Inflammation/Immunology
Target:
Synonyms: N-FMOC-leucine-d3; NPC 15199-d3; NSC 334290-d3
Synonyms: 13-Methylberberinium chloride
Category:
Alkaloids Ranunculaceae Coptis chinensis Franch. Metabolic Disease Plants Disease Research Fields Isoquinoline Alkaloids
Target:
Cat. No.: HY-N4103R
CAS No.: 17605-67-3
Cat. No.: HY-N1984R
CAS No.: 80286-58-4
Synonyms: Qing Hao acid (Standard); Artemisinic acid (Standard); Arteannuic acid (Standard)
Cat. No.: HY-178958
CAS No.: 3122526-69-3
Research Areas:
PPAR agonist 7 is an orally active pan-PPAR agonist, demonstrating potent activation of all three subtypes, PPARα (EC50 = 1.51 μM), PPARδ (EC50 = 1.11 μM), and PPARγ (EC50 = 3.14 μM). PPAR agonist 7 significantly enhances glucose uptake in adipocytes while exhibiting minimal adipogenic activity. PPAR agonist 7 can suppress PPARγ Ser273 phosphorylation in white adipose tissue and upregulate insulin-sensitizing genes. PPAR agonist 7 does not cause weight gain or fluid retention in high-fat diet (HFD)/
Streptozotocin (HY-13753) (STZ)-induced type 2 diabetes mellitus (T2DM) models. PPAR agonist 7 has selective modulation of PPAR signaling pathways without activation of adipogenic gene programs. PPAR agonist 7 can be used for the study of diabetes .
Cat. No.: HY-114335
CAS No.: 857906-76-4
Cat. No.: HY-123503
CAS No.: 1887055-63-1
Category:
Cat. No.: HY-N3027R
CAS No.: 117230-33-8
Cat. No.: HY-168924
Research Areas:
Wnt/β-catenin activator 1 (Compound 5m) is the orally active activator for Wnt/β-catenin signaling pathway, that arrests cell cycle at G1 phase, inhibits early proliferation of adipocytes, and inhibits adipogenesis in cell 3T3-L1 with an IC50 of 330 nM. Wnt/β-catenin activator 1 exhibits anti-adipogenic and anti-dyslipidemic activities in high-fat diet fed Syrian golden hamster model .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
