1190594-22-9
1190594-22-9
Chemical Structure
Fmoc-leucine-d10
- CAS No.: 1190594-22-9
- Formula:C21H13D10NO4
- Molecular Weight:363.47
InChIKey: CBPJQFCAFFNICX-QDXFTFMQSA-N
SMILES: [2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])C([2H])([2H])[C@](C(O)=O)([2H])NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O
Biological Activity: Fmoc-leucine-d10 is the deuterium labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Fmoc-leucine-d10 | 99.40% | Fmoc-leucine-d10 is the deuterium labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity. | ||||||||||||||||||||
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Fmoc-leucine (Standard) | ≥98% | Fmoc-leucine (Standard) is the analytical standard of Fmoc-leucine (HY-101064). This product is intended for research and analytical applications. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity. | ||||||||||||||||||||
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Fmoc-leucine-15N | 98.5% | Fmoc-leucine-15N is a 15N-labeled and 15N-labled Fmoc-leucine (HY-101064). | ||||||||||||||||||||
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Fmoc-leucine-13C6,15N | 95.12% | Fmoc-leucine-13C6,15N is a 15N-labeled and 13C-labled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity | ||||||||||||||||||||
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Fmoc-leucine-13C | 99.90% | Fmoc-leucine-13C is a 13C-labeled Boc-GlycineFmoc-leucine (HY-101064). | ||||||||||||||||||||
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Fmoc-leucine-d3 | 99.25% | Fmoc-leucine-d3 is the deuterium labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity. | ||||||||||||||||||||
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Fmoc-leucine | 99.9% | Fmoc-Leucine (N-FMOC-leucine) is an anti-inflammatory agent that not only promotes extracellular Ca2+ influx but also facilitates intracellular Ca2+ release. Fmoc-Leucine is a selective ligand for PPARγ (Ki = 15 μM), exhibiting insulin-sensitizing effects but with weak fatogenic activity. Fmoc-Leucine exhibits unique self-assembly properties and can form transient gels, stable gels, or crystals/2D sheets through different pathways. Fmoc-Leucine can be used in the research of diabetes, colitis, and bladder cancer. | ||||||||||||||||||||
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References
