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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
antineoplastic drugs
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "antineoplastic drugs" in MCE Product Catalog:
859
859 Publications Verification
Cat. No.: HY-17394
CAS No.: 15663-27-1
Synonyms: cis-Platinum; CDDP; cis-Diaminodichloroplatinum
Research Areas:
Cisplatin (CDDP) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy .
20
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Busulfan is a potent alkylating antineoplastic agent. Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic agent .
Cat. No.: HY-W190927
CAS No.: 159857-70-2
Synonyms: MC-Val-Cit-PAB-Doxorubicin
Target:
Research Areas:
MC-Val-Cit-Doxorubicin (MC-Val-Cit-PAB-Doxorubicin) is drug-linker conjugate for ADC. The maleimide can conjugate with thiol containing molecules. Doxorubicin is an anthracycline antibiotic with antineoplastic activity
Cat. No.: HY-W010255
CAS No.: 611-73-4
Synonyms: Benzoylformic acid
Cat. No.: HY-B0245S
CAS No.: 116653-28-2
Research Areas:
Busulfan (Standard) is the analytical standard of Busulfan. This product is intended for research and analytical applications. Busulfan is a potent alkylating antineoplastic agent. Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic agent .
Synonyms: AMD473; ZD0473
Target:
Research Areas:
Picoplatin (AMD473) is a platinum-based antineoplastic agent. Picoplatin is specifically to circumvent thiol-mediated drug resistance by sterically hindering its reaction with glutathione (GSH) while still retaining the ability to form cytotoxic lesions with DNA .
Cat. No.: HY-P99334
CAS No.: 1165741-01-4
Synonyms: Anti-Human CD70 Recombinant Antibody; SGN-75
Research Areas:
Vorsetuzumab mafodotin (SGN-75) is an Auristatin-based anti-CD70 antibody-drug conjugate (ADC). Vorsetuzumab mafodotin consists of a humanized monoclonal antibody, Vorsetuzumab and an ADC cytotoxin MMAF. Vorsetuzumab mafodotin has antineoplastic activity .
Cat. No.: HY-152861
CAS No.: 2553413-86-6
Synonyms: TAK-676 free base
Dazostinag (TAK-676 free base) is an agonist of stimulator of interferon genes (STING) protein with antineoplastic activity. Dazostinag can serve as a playload to synthesis antibody-drug conjugates (ADCs) .
Cat. No.: HY-W010255R
CAS No.: 611-73-4
Synonyms: Benzoylformic acid (Standard)
Cat. No.: HY-W010255S
CAS No.: 1217089-53-6
Synonyms: Benzoylformic acid-d5
Cat. No.: HY-145636
CAS No.: 2490556-51-7
Synonyms: AEX4089DC1; MGC018
Target:
Research Areas:
Vobramitamab duocarmazine (AEX4089DC1; MGC018), a humanized antibody-drug conjugate (ADC) targeted against B7-H3 (CD276). Vobramitamab duocarmazine is comprised of the cleavable linker-Duocarmycin payload, Vc-seco-DUBA (HY-128957), conjugated to an anti-B7-H3 humanized IgG1κ monoclonal antibody. Vobramitamab duocarmazine has antineoplastic activity .
Cat. No.: HY-W010255AS
CAS No.: 2708283-39-8
Synonyms: Benzoylformic acid-d5sodium; Sodium phenylglyoxylate-d5
Cat. No.: HY-119340
CAS No.: 87626-55-9
Synonyms: Flavoneacetic acid
Target:
Research Areas:
Mitoflaxone (flavoneacetic acid) is a synthetic flavonoid compound with vascular targeting properties. Mitoflaxone exerts anti-proliferative effects on endothelial cells through a superoxide-dependent mechanism, this effect leads to changes in the permeability of tumor blood vessels, thereby exerting anti-tumor effects [1] [2] .
Cat. No.: HY-16372
CAS No.: 227619-96-7
Synonyms: OSI-461
Target:
Research Areas:
CP-461 (OSI-461) is a selective apoptotic antineoplastic drug (SAAND) by engaging tubulin on colchicine site
Cat. No.: HY-W010255A
CAS No.: 43165-51-1
Synonyms: Benzoylformic acid sodium
Research Areas:
Phenylglyoxylic acid sodium (Benzoylformic acid sodium) is a metabolite of ethylbenzene and styrene (EB/S) and can be used as a biomarker of exposure to EB/S in human. Phenylglyoxylic acid sodium can be used as drug intermediate for synthesis of antineoplastic compounds .
Cat. No.: HY-13550A
CAS No.: 70711-40-9
Synonyms: NSC 196473 acetate; NSC 290813 acetate
Target:
Research Areas:
Ametantrone acetate (NSC 196473 acetate) is an antineoplastic drug with topoisomerase II inhibitory activity. Ametantrone acetate causes covalent cross-linking of DNA. The pharmacokinetic profile of Ametantrone acetate has been confirmed in clinical trials, and its elimination pathway in the body indicates the existence of a major metabolic pathway .
Cat. No.: HY-W750144
CAS No.: 3004488-90-5
Synonyms: Benzoylformic acid-13C8
Cat. No.: HY-U00279B
CAS No.: 6514-85-8
Target:
Research Areas:
Nitracrine hydrochloride is a platinum-based antineoplastic drug with selective toxicity to hypoxic cells. Nitracrine hydrochloride exhibits significant cytotoxicity against the Chinese hamster ovary cell line AA8 under hypoxic conditions. Nitracrine hydrochloride exerts its effect by binding to the insertion of DNA and forming covalent adducts. The cytotoxicity of Nitracrine hydrochloride under hypoxic conditions is related to its reductive metabolism to form alkylated substances. At the same time, it may enhance the reactivity to DNA through the insertion of DNA, thereby improving the efficacy. Nitracrine hydrochloride can also inhibit RNA synthesis, contributing to its anti-tumor effect .
Cat. No.: HY-124336
CAS No.: 152247-02-4
Target:
Research Areas:
CP 80080 is a Topoisomerase II ligand with almost no ability to stimulate topoisomerase II-mediated DNA cleavage. CP 80080 competes with DNA cleavage-enhancing antineoplastic agents for a common binding domain on Drosophila topoisomerase II, thereby attenuating the ability of these agents to stimulate topoisomerase II-mediated DNA cleavage. CP 80080 can be used in cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
