70711-40-9
Chemical Structure
Ametantrone acetate
Synonym(s): NSC 196473 acetate; NSC 290813 acetate
- CAS No.: 70711-40-9
- Formula:C26H36N4O8
- Molecular Weight:532.59
IUPAC Name: 1,4-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione diacetate
InChIKey: IGCAUIJHGNYDKE-UHFFFAOYSA-N
SMILES: O=C1C2=C(C(C3=C(C=CC(NCCNCCO)=C13)NCCNCCO)=O)C=CC=C2.CC(O)=O.CC(O)=O
Biological Activity: Ametantrone acetate (NSC 196473 acetate) is an antineoplastic drug with topoisomerase II inhibitory activity. Ametantrone acetate causes covalent cross-linking of DNA. The pharmacokinetic profile of Ametantrone acetate has been confirmed in clinical trials, and its elimination pathway in the body indicates the existence of a major metabolic pathway[1].
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Ametantrone acetate | Ametantrone acetate (NSC 196473 acetate) is an antineoplastic drug with topoisomerase II inhibitory activity. Ametantrone acetate causes covalent cross-linking of DNA. The pharmacokinetic profile of Ametantrone acetate has been confirmed in clinical trials, and its elimination pathway in the body indicates the existence of a major metabolic pathway. | |||||||||||||||||||||
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