CP 80080
CP 80080 is a Topoisomerase II ligand with almost no ability to stimulate topoisomerase II-mediated DNA cleavage. CP 80080 competes with DNA cleavage-enhancing antineoplastic agents for a common binding domain on Drosophila topoisomerase II, thereby attenuating the ability of these agents to stimulate topoisomerase II-mediated DNA cleavage. CP 80080 can be used in cancer-related research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 152247-02-4
- 分子式: C20H16FNO4
- 分子量:353.34
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Topoisomerase II |
化学情報
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CAS 番号 152247-02-4
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分子量 353.34
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分子式 C20H16FNO4
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SMILES
O=C(C1=CN(C2CC2)C3=C(C=C(F)C(C4=CC=C(OC)C=C4)=C3)C1=O)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Elsea SH, et al. Quinolones share a common interaction domain on topoisomerase II with other DNA cleavage-enhancing antineoplastic drugs. Biochemistry. 1997 Mar 11;36(10):2919-24. [Content Brief]
[2]. Osheroff N, et al. Defining functional drug-interaction domains on topoisomerase II by exploiting mechanistic differences between drug classes. Cancer chemotherapy and pharmacology. 1994;34 Suppl:S19-25. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CP 80080 関連分類
HY-124336 関連分類
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