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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
chronic visceral pain
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "chronic visceral pain" in MCE Product Catalog:
Cat. No.: HY-P2786A
CAS No.: 741738-57-8
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Cat. No.: HY-P5907
CAS No.: 2883653-86-7
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Cat. No.: HY-P5865
Synonyms: Theraphotoxin-Tap1a; TRTX-Tap1a; µ/ω-TRTX-Tap1a
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Cat. No.: HY-189273
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Nav1.8-IN-25 is a NaV1.8 inhibitor (IC50 of 3.43 μM for resting-state NaV1.8 and IC50 of 3.37 μM for half-inactivated NaV1.8). It exerts analgesic activity in inflammatory, neuropathic, and visceral pain models by blocking voltage-gated Sodium Channel currents in both resting and half-inactivated states. Nav1.8-IN-25 can be used for research on chronic pain .
Cat. No.: HY-181612
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COX-2/CaV2.2-IN-1 is an orally active and selective dual COX-2/CaV2.2 inhibitor, exhibiting a COX-2 IC50 of 0.26 μM and a CaV2.2 IC50 of 0.29 μM. COX-2/CaV2.2-IN-1 suppresses inflammatory responses and inflammatory mediator (IL-6, TNF-α, NO) production. COX-2/CaV2.2-IN-1 produces pronounced analgesic effects in diverse models of inflammatory, neuropathic, and visceral pain. COX-2/CaV2.2-IN-1 can be used for the research of chronic pain .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
