2 Results for "

cpm1285

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "cpm1285" in MCE Product Catalog:

Cat. No.: HY-P10057
CAS No.: 300349-97-7
Target:  

Apoptosis

Research Areas:  

Cancer

cpm-1285 induces apoptosis by functionally blocking intracellular Bcl-2 and related death antagonists. cpm-1285 shows strong binding potency to Bcl-2 with an IC50 value of 130 nM. cpm-1285 reduces tumor burden in mice .
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Cat. No.: HY-P10058
Research Areas:  

Cancer

cpm-1285m is a cell-permeable mutated peptide analogue of cpm-1285 (Bcl-2 inhibitory peptide). cpm-1285m contains a single substitution of alanine for Leu-151, and exhibits a decrease in Bcl-2 binding affinity with a reduction in IC50 of ∼15-fold. cpm-1285m can be used as a control of cpm-1285 .
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