Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
cyclophilin D (CypD)
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "cyclophilin D (CypD)" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-N1511
CAS No.: 108340-60-9
Cat. No.: HY-157088
Purity: 99.49%
Target:
Research Areas:
C105SR is a cyclophilin D (CypD) inhibitor targeting to peptidyl-prolylcis-trans isomerase (PPIase). C105SR inhibits mitochondrial permeability transition opening (mPTP) with an IC 50 of 5 nM. C105SR inhibits hypoxia and reoxygenation inudced hepatocyte apoptosis and increases the level of calcium retention capacity (CRC). C105SR exhibits hepaprotective effect in ischaemia-reperfusion injury (IRI) mouse model .
Cat. No.: HY-151487
CAS No.: 2651994-75-9
Target:
Research Areas:
CypD-IN-3 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-3 has CypD affinity with an IC50 value of 0.01 μM. CypD-IN-3 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes .
Cat. No.: HY-151488
CAS No.: 3023438-19-6
Target:
Research Areas:
CypD-IN-4 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-4 has CypD affinity with an IC50 value of 0.057 μM. CypD-IN-4 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes .
Cat. No.: HY-116095
CAS No.: 1572646-93-5
Target:
Research Areas:
CypD-IN-5 (compound C-9) is a potent cyclophilin D (CypD) inhibitor. CypD-IN-5 can be used in the study of Alzheimer's disease .
Cat. No.: HY-N1511R
CAS No.: 108340-60-9
Target:
Cat. No.: HY-151489
CAS No.: 3023438-33-4
Target:
Research Areas:
CypE-IN-1 is a potent and subtype-selective cyclophilin E (CypE) inhibitor. CypE-IN-1 has CypE affinity with IC50 and Ki values of 0.013 μM and 0.072 μM, respectively. CypE-IN-1 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes .
Cat. No.: HY-179416
Target:
Research Areas:
CypD-IN-6 is a potent cyclophilin D (CypD/PPIF) inhibitor that inhibits CypD PPIase activity (Ki = 32 nM) and binds to CypD (Kd = 60 nM). CypD-IN-6 can be used for mitochondrial permeability transition pore (MPTP) related disease research such as ischemia-reperfusion injury and acute pancreatitis 1.
Cat. No.: HY-179417
Target:
Research Areas:
CypD-IN-7 is a potent cyclophilin D (CypD/PPIF) inhibitor that inhibits CypD PPIase activity (K i = 2.4 nM) and provides protection against mitochondrial permeability transition pore (MPTP) opening. CypD-IN-7 can be used for pancreatitis research .
Cat. No.: HY-P74211A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPIF; HCyP3; Peptidylprolyl Isomerase F; CyP-M; CypD; CYP3; cyclophilin D; Peptidyl-Prolyl Cis-Trans Isomerase, Mitochondrial; Cyp-D; Peptidylprolyl Isomerase F (cyclophilin F); Peptidyl-Prolyl Cis-Trans Isomerase F, Mitochondrial; Peptidyl-Prolyl Cis-Tra
Species:
Human
Source:
HEK293
Cat. No.: HY-P74211
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPIF; HCyP3; Peptidylprolyl Isomerase F; CyP-M; CypD; CYP3; cyclophilin D; Peptidyl-Prolyl Cis-Trans Isomerase, Mitochondrial; Cyp-D; Peptidylprolyl Isomerase F (cyclophilin F); Peptidyl-Prolyl Cis-Trans Isomerase F, Mitochondrial; Peptidyl-Prolyl Cis-Tra
Species:
Human
Source:
HEK293
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
