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cytochrome P450 monooxygenase

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By Targets:	Cytochrome P450 (5) Biochemical Assay Reagents (1) Drug Intermediate (1) Endogenous Metabolite (3) Environmental Pollutants (1) Fungal (1) Glutathione S-transferase (2) Insecticide (1) Reference Standards (2) Sodium Channel (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Infection (2) Metabolic Disease (3)

12

Inhibitors & Agonists

4

Natural
Products

2

Recombinant Proteins

5

Antibodies

Targets Recommended: Cytochrome P450 Squalene Monooxygenase KMO Dopamine β-hydroxylase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Glucoraphenin potassium	Glutathione S-transferase Cytochrome P450	Metabolic Disease
Glucoraphenin potassium is an orally effective glucosinolate. Glucoraphenin potassium can be isolated from radish sprouts. Glucoraphenin potassium enhances the enzymatic activity of Glutathione S-transferase. Glucoraphenin potassium enhances the activity of cytochrome *P450*-related monooxygenase .

Dipropyl disulfide Propyl Disulfide; DPDS	Environmental Pollutants Cytochrome P450	Others
Dipropyl disulfide is oxidized to dipropyl thiosulfinate (DPDSO) by rat microsomes. Both flavincontaining monooxygenases (FMO) and cytochrome P450 enzymes (CYPs) are involved in dipropyl disulfide oxidation. Dipropyl disulfide forms two metabolites: propylglutathione sulfide conjugate and propylthiol .

Cytochrome P450	Endogenous Metabolite	Metabolic Disease Cancer
Cytochrome P450 is a family of monooxygenase enzymes that catalyzes the conversion of fatty acids to terminal alkenes using hydrogen peroxide as a cosubstrate. Cytochrome P450 as membrane-bound hemoproteins, plays important roles in the detoxification of drugs, cellular metabolism, and homeostasis .

Benzobarbital	Cytochrome P450	Cardiovascular Disease Metabolic Disease
Benzobarbital is an active low-toxicity inductor of the liver *monooxygenase* system. Benzobarbital raises **cytochrome P-450** concentration. Benzobarbital can be used in the research of post-ischemic liver disease .

Seneciphylline (Standard)	Reference Standards Glutathione S-transferase Cytochrome P450	Cancer
Seneciphylline (Standard) is the analytical standard of Seneciphylline. This product is intended for research and analytical applications. Seneciphylline is a toxic pyrrolizidine alkaloid in Gynura japonica . Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities .

18-HETE	Endogenous Metabolite	Others
18-HETE (compound 3) is a monooxygenase metabolite of cytochrome P450 (CYP450).18- HETE consists of arachidonic acid bearing a hydroxy substituent at position 18 .

7-Deoxyloganin	Biochemical Assay Reagents	Others
7-Deoxyloganin serves as a biosynthetic precursor of Loganin (HY-N0512). 7-Deoxyloganin undergoes hydroxylation catalyzed by 7-deoxyloganin 7-hydroxylase, a cytochrome P450-dependent monooxygenase, to produce Loganin .

HY-W196803R

Dipropyl disulfide (Standard) Propyl Disulfide (Standard); DPDS (Standard)	Cytochrome P450 Reference Standards	Others
Dipropyl disulfide is oxidized to dipropyl thiosulfinate (DPDSO) by rat microsomes. Both flavincontaining monooxygenases (FMO) and cytochrome P450 enzymes (CYPs) are involved in dipropyl disulfide oxidation. Dipropyl disulfide forms two metabolites: propylglutathione sulfide conjugate and propylthiol .

E-α-Bisabolene	Endogenous Metabolite Fungal	Infection
E-α-Bisabolene is a non-cyclic sesquiterpene. E-α-Bisabolene holds a central position in the metabolic network of Phanerochaete chrysosporium. E-α-Bisabolene can be utilized by white-rot fungi for the biosynthesis of secondary metabolites .

m-Terphenyl	Drug Intermediate	Others
m-Terphenyl is a non-chlorinated trisphenyl compound and is commonly used as the basic structure for industrial raw materials (such as plastic additives). In liver enzyme induction experiments, m-Terphenyl exhibits weak activity and is unable to significantly activate the cytochrome P-450-dependent monooxygenase system .

C5F2-HCB		Cancer
C5F2-HCB is a CYP-mediated inhibitor of the biosynthesis of arachidonic acid epoxygenase product (±) 14,15-EET (HY-150084), with an IC₅₀ of 3.1 μM. C5F2-HCB inhibits EET-driven oxidative phosphorylation (OXPHOS) associated with tumor hypoxia, converting an immunologically "cold" tumor microenvironment into a "hot" one. C5F2-HCB reverses the immune-excluded tumor microenvironment in ER ⁺HER2 ⁻ breast cancer allograft models. C5F2-HCB can be used in research related to ER ⁺HER2 ⁻ breast cancer .

Zeta-Cypermethrin	Insecticide Sodium Channel	Infection
Zeta-Cypermethrin is a type II pyrethroid insecticide. Zeta-Cypermethrin primarily acts on voltage-gated sodium channels in nerve cells, causing delayed channel closure, persistent nerve excitation and convulsions. In Drosophila, Zeta-Cypermethrin rapidly induces extremely high metabolic resistance that can be screened, and exhibits in vitro genotoxicity to human peripheral blood lymphocytes .

Species:	Human (1)
Tag:	SUMO (1) His (2)
Source:	P. pastoris (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

	CYP102A1 Protein, Priestia megaterium (P. pastoris, His) Bifunctional cytochrome P450; NADPH--P450 reductase; cytochrome P450BM-3; Fatty acid monooxygenase; Flavocytochrome P450 BM3	Others	P. pastoris
	The CYP102A1 protein acts as a fatty acid monooxygenase, catalyzing the hydroxylation of fatty acids at various positions. The protein also exhibits NADPH-dependent reductase activity, promoting electron transfer within its domain. CYP102A1 Protein, Priestia megaterium (P. pastoris, His) is the recombinant CYP102A1 protein, expressed by P. pastoris , with C-6*His labeled tag.

	CYP11A1 Protein, Human (His, SUMO) Cholesterol 20 22 desmolase; Cholesterol desmolase; Cholesterol monooxygenase (side chain cleaving); Cholesterol side chain cleavage enzyme; Cholesterol side chain cleavage enzyme mitochondrial; Cholesterol side-chain cleavage enzyme; CP11A_HUMAN; CYP11A; CYP11A1; CYPXIA1; cytochrome P450 11A1; cytochrome P450 11A1 mitochondrial; cytochrome P450 family 11 subfamily A polypeptide 1; cytochrome P450 subfamily XIA; cytochrome P450(scc); cytochrome P450C11A1; mitochondrial; P450SCC; Steroid 20 22 lyase	Human	E. coli

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Host:	Mouse (2) Rabbit (3)
Reactivity:	Human (5) Rat (1) Mouse (2) Golden hamster (1)
Application:	IHC-P (1) ICC/IF (2) IHC-F (1) WB (5) FC (1)
Isotype:	IgG (3)
Conjugation:	Non-conjugated (5)
Clonality:	Polyclonal (2) Monoclonal (3) Recombinant (1)
Modification:	Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

	Cytochrome P450 1A2 Antibody (YA3505) cytochrome P450 1A2; cytochrome P450, family 1, subfamily a, polypeptide 2; cytochrome P450 family 1 polypeptide 2; cytochrome P450 subfamily I aromatic compound inducible polypeptide 2; Cyp1a2; CYPD45; P-450d; RATCYPD45; CP12; CP 12; P3-450; Aryl hydrocarbon hydroxylase; Dioxin inducable P3 45; Flavoprotein linked monooxygenase; Microsomal monooxygenase; P450 4; P450 form 4; P450 P3; P450(PA); Xenobiotic monooxygenase; P450 1A2.	WB, ICC/IF, FC	Human
	Cytochrome P450 1A2 Antibody (YA3505) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome P450 1A2.

	Cytochrome P450 17A1 Antibody (YA5258) 20 lyase; CP17A_HUMAN; CPT7; CYP17; CYP17A1; CYPXVII; cytochrome P450 17A1; cytochrome P450 family 17; cytochrome P450 family 17 subfamily A polypeptide 1; cytochrome P450 subfamily XVII; steroid 17 alpha hydroxylase; adrenal hyperplasia; cytochrome P450 XVIIA1; cytochrome P450-C17; cytochrome P450c17; OTTHUMP00000020382; P450 C17; P450c17; S17AH; Steroid 17 alpha hydroxylase/17,20 lyase; Steroid 17 alpha monooxygenase; Steroid 17-alpha-hydroxylase/17; Steroid 17-alpha-monooxygenase.	WB	Human
	Cytochrome P450 17A1 Antibody (YA5258) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Cytochrome P450 17A1.

	CYP11A1 Antibody 2 Publications Verification Cholesterol 20 22 desmolase antibody Cholesterol desmolase antibody; Cholesterol monooxygenase (side chain cleaving) antibody; Cholesterol side chain cleavage enzyme antibody; Cholesterol side chain cleavage enzyme mitochondrial antibody; Cholesterol side-chain cleavage enzyme antibody; CP11A_HUMAN antibody; CYP11A antibody; CYP11A1 antibody; CYPXIA1 antibody; cytochrome P450 11A1 antibody; cytochrome P450 11A1 mitochondrial antibody; cytochrome P450 family 11 subfamily A polypeptide 1 antibody; cytochrome P450 subfamily XIA antibody; cytochrome P450(scc) antibody; cytochrome P450C11A1 antibody; mitochondrial antibody; P450SCC antibody; Steroid 20 22 lyase antibody;	WB, IHC-P, IHC-F, ICC/IF	Human, Mouse, Rat
	CYP11A1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to CYP11A1.

	CYP7A1 Antibody CYP7A1; CYP7; Cholesterol 7-alpha-monooxygenase; CYPVII; Cholesterol 7-alpha-hydroxylase; cytochrome P450 7A1	WB	Human, Mouse
	CYP7A1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to CYP7A1.

	CYP7A1 Antibody (YA5117) CYP7A1; CYP7; Cholesterol 7-alpha-monooxygenase; CYPVII; Cholesterol 7-alpha-hydroxylase; cytochrome P450 7A1	WB	Human, Golden hamster
	CYP7A1 Antibody (YA5117) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CYP7A1.

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