Glucoraphenin potassium
Based on 1 Customer Validation
Glucoraphenin potassium is an orally effective glucosinolate. Glucoraphenin potassium can be isolated from radish sprouts. Glucoraphenin potassium enhances the enzymatic activity of Glutathione S-transferase. Glucoraphenin potassium enhances the activity of cytochrome P450-related monooxygenase.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 108844-81-1
- Formula: C12H20KNO10S3
- Molecular Weight:473.58
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
XME[2]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Sprague Dawley (male, 280 g)[1]
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Dosage:24 mg/kg (single dose; repeated daily for four days); 120 mg/kg (single dose; repeated daily for four days)
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Administration:p.o.; single dose; daily for four consecutive days
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Result:Increased CYP3A1/2-linked aminopyrine N-demethylase activity to 9.67 nmol mg-1 min-1 (single 24 mg/kg), 9.67 nmol mg-1 min-1 (single 120 mg/kg), 7.11 nmol mg-1 min-1 (repeated 24 mg/kg), and 7.22 nmol mg-1 min-1 (repeated 120 mg/kg) from control 5.50 nmol mg-1 min-1.
Increased CYP1A2-linked methoxyresorufin O-demethylase activity to 20.67 pmol mg-1 min-1 (single 24 mg/kg) and 17.90 pmol mg-1 min-1 (repeated 24 mg/kg) from control 10.33 pmol mg-1 min-1; slightly increased it to 11.71 pmol mg-1 min-1 (single 120 mg/kg), while repeated 120 mg/kg showed no significant change.
Showed no significant changes in CYP1A1-linked ethoxyresorufin O-deethylase activity across any dose or schedule compared to control 33.34 pmol mg-1 min-1.
Chemical Information
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CAS No. 108844-81-1
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Appearance Solid
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Molecular Weight 473.58
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Formula C12H20KNO10S3
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Color White to off-white
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SMILES
CS(/C=C/CC/C(S[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)=N/OS(=O)(O[K])=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)