19 Results for "

desamino-metamitron

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "desamino-metamitron" in MCE Product Catalog:

4
4 Cited Publications
Art. -Nr.: HY-P2336A
Target:  

Melanocortin Receptor

Forschungsgebiete:  

Cancer

CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
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1
1 Cited Publications
Art. -Nr.: HY-105055
CAS. Nr.: 77327-05-0
Reinheit:  99.95%
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
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Art. -Nr.: HY-P4070
CAS. Nr.: 1188379-43-2
Target:  

Insulin Receptor

Forschungsgebiete:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
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Art. -Nr.: HY-P5362
NODAGA-LM3 is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
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Art. -Nr.: HY-W014793
CAS. Nr.: 41394-05-2
Target:  

Herbicide

Forschungsgebiete:  

Others

Metamitron is a triazinone pre-emergence and post-emergence Herbicide and fruit thinner. Metamitron controls broadleaf weeds and grassy weeds. Metamitron induces fruit drop in peach trees, and promotes fruit drop, reduces yield per plant, and increases the proportion of large fruits in apple trees. Metamitron is applicable to research related to the management of broadleaf weeds, grassy weeds, and temperate fruit tree crops .
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Art. -Nr.: HY-P10341
CAS. Nr.: 1345835-12-2
Target:  

GCGR

Forschungsgebiete:  

Metabolic Disease

ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .
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Art. -Nr.: HY-P11004
Target:  

Bacterial Antibiotic

Forschungsgebiete:  

Infection

A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .
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Art. -Nr.: HY-P10472
CAS. Nr.: 134457-28-6
Target:  

GnRH Receptor

Forschungsgebiete:  

Endocrinology

Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .
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Art. -Nr.: HY-P4757
CAS. Nr.: 108081-77-2
Target:  

Parasite

Forschungsgebiete:  

Others

N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
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Art. -Nr.: HY-P11243
Target:  

Ephrin Receptor

Forschungsgebiete:  

Neurological Disease

EphA4 agonist compound 23 is a novel EphA4 agonist peptide mimic. EphA4 agonist compound 23 exhibits high affinity, high selectivity, and significant receptor activation ability. EphA4 agonist compound 23 is commonly used in the study of neurodegenerative diseases .
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Art. -Nr.: HY-P2434
CAS. Nr.: 846569-60-6
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .
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Art. -Nr.: HY-P5362A
NODAGA-LM3 TFA is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 TFA does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 TFA shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 TFA can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
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Art. -Nr.: HY-105168
CAS. Nr.: 157380-72-8
Target:  

Endothelin Receptor

Forschungsgebiete:  

Cardiovascular Disease

TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
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Art. -Nr.: HY-P2075
CAS. Nr.: 126784-34-7
Target:  

Renin

Forschungsgebiete:  

Endocrinology

EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .
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Art. -Nr.: HY-P10876
Target:  

Amyloid-β

Forschungsgebiete:  

Neurological Disease

mcK6A1 is an inhibitor for the aggregation of amyloid-β (), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .
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Art. -Nr.: HY-P11901
Target:  

Ras HDAC Apoptosis

Forschungsgebiete:  

Cancer

KH-1 is a KRAS G12D/HDAC2 dual-target inhibitor with Kd values of 11.63 nM and 20.17 nM, respectively. KH-1 induces pancreatic cell apoptosis, cell cycle arrest, and inhibits cell proliferation, invasion and migration, as well as suppresses tumor growth in pancreatic cancer xenograft models. KH-1 can be used for the research of pancreatic cancer .
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Art. -Nr.: HY-P11823
Target:  

Fluorescent Dye

Forschungsgebiete:  

Inflammation/Immunology Cancer

FAPα/DPP4 fluorogenic substrate-1 is a fluorogenic macrocyclic peptide substrate that can be cleaved by FAPα and DPP4. FAPα/DPP4 fluorogenic substrate-1 can be used in the research of cancer and type 2 diabetes .
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Art. -Nr.: HY-P11488
JR11-PEG3-DOTA-PSMA-03 (Compound 2) is an RDC-related compound containing the chelating agent DOTA (HY-W053583), the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-DOTA-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 94.0 nM, 81.8 nM, respectively. JR11-PEG3-DOTA-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-DOTA-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
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Art. -Nr.: HY-P11485
JR11-PEG3-HBED-CC-PSMA-03 (Compound 1) is an RDC-related compound containing the chelating agent HBED-CC, the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-HBED-CC-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 59.2 nM, 57.0 nM, respectively. JR11-PEG3-HBED-CC-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-HBED-CC-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
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