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Results for "

dihydropteroate

" in MedChemExpress (MCE) Product Catalog:

29

Inhibitors & Agonists

1

Natural
Products

9

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0322
    Sulfamethoxazole
    Maximum Cited Publications
    24 Publications Verification

    Ro 4-2130

    		 Antibiotic Bacterial Infection Cancer
    Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .
    Sulfamethoxazole
  • HY-B0322S
    Sulfamethoxazole-d4
    1 Publications Verification

    Ro 4-2130-d4

    		 Isotope-Labeled Compounds Antibiotic Bacterial Infection
    Sulfamethoxazole-d4 (Ro 4-2130-d4) is a deuterium labeled Sulfamethoxazole (HY-B0322). Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .
    Sulfamethoxazole-d4
  • HY-B0212
    Sulfapyridine
    2 Publications Verification

    		 Bacterial Antibiotic Infection Inflammation/Immunology
    Sulfapyridine, a major metabolite of Sulfasalazine, is a sulfonamide antibiotic agent. Sulfapyridine inhibits recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. Sulfapyridine has antibacterial, anti-inflammatory and anti-rheumatic activities .
    Sulfapyridine
  • HY-B0322A
    Sulfamethoxazole sodium
    Maximum Cited Publications
    24 Publications Verification

    Ro 4-2130 sodium

    		 Antibiotic Bacterial Infection
    Sulfamethoxazole (Ro 4-2130) sodium is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole sodium inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole sodium can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .
    Sulfamethoxazole sodium
  • HY-141619
    Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:5)
    1 Publications Verification

    		 Bacterial Infection
    Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:5), an antibacterial agent, is a Trimethoprim (HY-B0510) and Sulfamethoxazole (HY-B0322) mixture. The ratio of Trimethoprim to Sulfamethoxazole in the combination mixture is 1 : 5 .
    Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:5)
  • HY-B0946
    Sulfamonomethoxine
    1 Publications Verification

    		 Antibiotic Bacterial Infection
    Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .
    Sulfamonomethoxine
  • HY-B0333
    Sulfamethizole
    2 Publications Verification

    		 Antibiotic Bacterial Infection
    Sulfamethizole is a sulfathiazole antibiotic. Sulfamethizole inhibits the synthesis of folic acid and thymine, and selectively suppresses Photobacterium phosphoreum bioluminescence. Sulfamethizole exerts antibacterial activity against Escherichia coli-mediated urinary tract infections but no activity against sulII gene-positive Escherichia coli. Sulfamethizole is applicable for the research of urinary tract infections and Photobacterium phosphoreum bioluminescence mechanisms .
    Sulfamethizole
  • HY-107923
    Sulfisoxazole acetyl

    N1-Acetylsulfisoxazole

    		 Bacterial Infection
    Sulfisoxazole acetyl (N1-Acetylsulfisoxazole), a Sulfisoxazole derivative, is an orally active dihydropteroate synthase inhibitor. Sulfisoxazole acetyl has an antibacterial action .
    Sulfisoxazole acetyl
  • HY-B0322R
    Sulfamethoxazole (Standard)

    Ro 4-2130 (Standard)

    		 Reference Standards Antibiotic Bacterial Infection
    Sulfamethoxazole (Standard) (Ro 4-2130 (Standard)) is the analytical standard of Sulfamethoxazole (HY-B0322). This product is intended for research and analytical applications. Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis.
    Sulfamethoxazole (Standard)
  • HY-B0322AR
    Sulfamethoxazole sodium (Standard)

    Ro 4-2130 sodium (Standard)

    		 Reference Standards Antibiotic Bacterial Infection Cancer
    Sulfamethoxazole (Standard) (Ro 4-2130 (Standard)) sodium is the analytical standard of Sulfamethoxazole sodium (HY-B0322A). This product is intended for research and analytical applications. Sulfamethoxazole (Ro 4-2130) sodium is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole sodium inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole sodium can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis.
    Sulfamethoxazole sodium (Standard)
  • HY-B0322S1
    Sulfamethoxazole-13C6

    Ro 4-2130-13C6

    		 Isotope-Labeled Compounds Antibiotic Bacterial Infection
    Sulfamethoxazole- 13C6 (Ro 4-2130- 13C6) is a 13C labeled Sulfamethoxazole (HY-B0322). Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .
    Sulfamethoxazole-13C6
  • HY-B0322B
    Sulfamethoxazole 1000 µg/mL in methanol
    20+ Cited Publications

    Ro 4-2130 1000 µg/mL in methanol

    		 Antibiotic Bacterial Infection
    Sulfamethoxazole (Ro 4-2130) 1000 μg/mL in methanol is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole 1000 μg/mL in methanol inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole 1000 μg/mL in methanol can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .
    Sulfamethoxazole 1000 µg/mL in methanol
  • HY-B0212R
    Sulfapyridine (Standard)

    		Reference Standards Bacterial Antibiotic Infection Inflammation/Immunology
    Sulfapyridine (Standard) is the analytical standard of Sulfapyridine. This product is intended for research and analytical applications. Sulfapyridine, a major metabolite of Sulfasalazine, is a sulfonamide antibiotic agent. Sulfapyridine inhibits recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. Sulfapyridine has antibacterial, anti-inflammatory and anti-rheumatic activities .
    Sulfapyridine (Standard)
  • HY-B0946S
    Sulfamonomethoxine-d4

    		Isotope-Labeled Compounds Antibiotic Bacterial Infection
    Sulfamonomethoxine-d4 is a deuterium labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .
    Sulfamonomethoxine-d4
  • HY-147721
    Dihydropteroate synthase-IN-1

    		Bacterial Infection
    Dihydropteroate synthase-IN-1 (compound 5g) is a potent dihydropteroate synthase (DHPS) inhibitor. Dihydropteroate synthase-IN-1 shows antimicrobial activities and antifungal activity. Dihydropteroate synthase-IN-1 inhibits cytochromes P450. Dihydropteroate synthase-IN-1 can bu used as diagnostic radio imaging material .
    Dihydropteroate synthase-IN-1
  • HY-101829
    Sulfaproxiline

    Sulfaproxylin; Sulfaproxyline

    		 Antibiotic Bacterial Infection
    Sulfaproxyline (Sulfaproxylin; Sulfaproxyline) is a sulfonamide antibiotic that inhibits bacterial dihydropteroate synthase, thereby blocking folate biosynthesis required for nucleic acid production. Sulfaproxyline shows antimicrobial activity primarily against Staphylococcus species and common uropathogens. Sulfaproxyline reduces bacterial growth by impairing DNA and protein synthesis. Sulfaproxyline can be used for research of staphylococcal and urinary tract infections .
    Sulfaproxiline
  • HY-W097570
    Sulfamonomethoxine sodium
    1 Publications Verification

    		 Antibiotic Bacterial Infection Neurological Disease
    Sulfamonomethoxine sodium is an orally active broad-spectrum synthetic sulfonamide antibiotic that inhibits dihydropteroate synthetase. Sulfamonomethoxine sodium increases blood glucose levels, induces anxiety-related activities and impairs spatial learning and memory. Sulfamonomethoxine sodium can be used for the research of anxiety, spatial memory impairment, colisepticemia, salmonellosis, and staphylococcus infection .
    Sulfamonomethoxine sodium
  • HY-B0273B
    Sulfadiazine 100 µg/mL in methanol
    5+ Cited Publications

    		 Parasite Bacterial Environmental Pollutants Infection
    Sulfadiazine 100 µg/mL in methanol is an orally active sulfonamide antibiotic. Sulfadiazine 100 µg/mL in methanol competitively inhibits p-aminobenzoic acid in the folic-acid-metabolism cycle, inhibiting multiplication of most Gram-positive and many Gram-negative bacteria. Sulfadiazine 100 µg/mL in methanol persists in soil long-term, and exerts selective pressure for sulfonamide-resistant microbial populations. Sulfadiazine 100 µg/mL in methanol targets Toxoplasma gondii DHPS enzyme. Sulfadiazine 100 µg/mL in methanol can be used for the research of congenital toxoplasmosis and bacterial infection .
    Sulfadiazine 100 µg/mL in methanol
  • HY-B0512S
    Sulfamerazine-d4

    RP2632-d4

    		 Isotope-Labeled Compounds Bacterial Infection
    Sulfamerazine-d4 is a deuterium labeled Sulfamerazine. Sulfamerazine, a sulfonamide antibacterial, inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes .
    Sulfamerazine-d4
  • HY-B0946R
    Sulfamonomethoxine (Standard)

    		Reference Standards Antibiotic Bacterial Infection
    Sulfamonomethoxine (Standard) is the analytical standard of Sulfamonomethoxine (HY-B0946). This product is intended for research and analytical applications. Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .
    Sulfamonomethoxine (Standard)
  • HY-B0242S1
    Sulfanilamide-d4

    Sulphanilamide-d4

    		 Bacterial Antibiotic Infection
    Sulfanilamide-d4 is the deuterium labeled Sulfanilamide. Sulfanilamide is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.
    Sulfanilamide-d4
  • HY-W097570R
    Sulfamonomethoxine sodium (Standard)

    		Bacterial Antibiotic Reference Standards Infection
    Sulfamonomethoxine (sodium) (Standard) is the analytical standard of Sulfamonomethoxine (sodium). This product is intended for research and analytical applications. Sulfamonomethoxine sodium is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate .
    Sulfamonomethoxine sodium (Standard)
  • HY-133668R
    Monoethyl phthalate (Standard)

    		Drug Metabolite Reference Standards Cancer
    Sulfamonomethoxine (sodium) (Standard) is the analytical standard of Sulfamonomethoxine (sodium). This product is intended for research and analytical applications. Sulfamonomethoxine sodium is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate .
    Monoethyl phthalate (Standard)
  • HY-B0946S1
    Sulfamonomethoxine-d3

    		Isotope-Labeled Compounds Antibiotic Bacterial Infection
    Sulfamonomethoxine-d3 is the deuterium labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .
    Sulfamonomethoxine-d3
  • HY-B0946S3
    Sulfamonomethoxine-d3-1

    		Isotope-Labeled Compounds Antibiotic Bacterial Infection
    Sulfamonomethoxine-d3-1 is the deuterium labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .
    Sulfamonomethoxine-d3-1
  • HY-B0946S2
    Sulfamonomethoxine-13C6

    		Isotope-Labeled Compounds Antibiotic Bacterial Infection
    Sulfamonomethoxine- 13C6 is the 13C6 labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .
    Sulfamonomethoxine-13C6
  • HY-B0512S1
    Sulfamerazine-13C6

    RP2632-13C6

    		 Isotope-Labeled Compounds Bacterial Antibiotic Infection
    Sulfamerazine- 13C6 (RP2632- 13C6) is 13C labeled Sulfamerazine (HY-B0512). Sulfamerazine (RP-2632) is a sulfonamide antibacterial. Sulfamerazine, the monomethyl derivative of sulfadiazine, is 2-sulfanilamido-4-methylpyrimidine. Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes.
    Sulfamerazine-13C6
  • HY-100010
    Sulfathiourea

    		Fungal Antifolate Infection
    Sulfathiourea is an inhibitor of Pneumocystis carinii dihydropteroate synthetase (dihydropteroate synthetase), with an IC50 of 0.022 μM and a Ki of 16.5 nM. Sulfathiourea blocks folate biosynthesis by inhibiting the enzyme that links 7,8-dihydro-6-hydroxymethylpterin pyrophosphate with p-aminobenzoic acid to form dihydropteroate. Sulfathiourea can be used in research related to *Pneumocystis carinii* pneumonia .
    Sulfathiourea
  • HY-135062
    9-Methylguanine

    		Bacterial Infection
    9-Methylguanine, a derivative of 8-mercaptoguanine, is a dihydropteroate synthase (DHPS) inhibitor with a Kd of 58 μM for E.coli DHPS (EcDHPS) .
    9-Methylguanine

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