144-83-2
144-83-2
Chemical Structure
Sulfapyridine
- CAS No.: 144-83-2
- Formula:C11H11N3O2S
- Molecular Weight:249.29
IUPAC Name: 4-amino-N-(pyridin-2-yl)benzenesulfonamide
InChIKey: GECHUMIMRBOMGK-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(N)C=C1)(NC2=NC=CC=C2)=O
Biological Activity: Sulfapyridine, a major metabolite of Sulfasalazine, is a sulfonamide antibiotic agent. Sulfapyridine inhibits recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. Sulfapyridine has antibacterial, anti-inflammatory and anti-rheumatic activities[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sulfapyridine | 99.85% | Sulfapyridine, a major metabolite of Sulfasalazine, is a sulfonamide antibiotic agent. Sulfapyridine inhibits recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. Sulfapyridine has antibacterial, anti-inflammatory and anti-rheumatic activities. | ||||||||||||||||||||
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Sulfapyridine (Standard) | 99.86% | Sulfapyridine (Standard) is the analytical standard of Sulfapyridine. This product is intended for research and analytical applications. Sulfapyridine, a major metabolite of Sulfasalazine, is a sulfonamide antibiotic agent. Sulfapyridine inhibits recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. Sulfapyridine has antibacterial, anti-inflammatory and anti-rheumatic activities. | ||||||||||||||||||||
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Sulfapyridine-d4 | 99.35% | Sulfapyridine-d4 a deuterium labeled Sulfapyridine. Sulfapyridine is a sulfonamide antibacterial. | ||||||||||||||||||||
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References
- [1]. Kazuki Omoteyama, et al. Effects of salazosulfapyridine on the profile of cell surface proteins, revealed by biotinylation of cell surface proteins and 2-dimentional electrophoresis. Biochim Biophys Acta Proteins Proteom. 2019 Jan;1867(1):47-56. [Content Brief]
- [2]. J J Andreasen, et al. In vitro susceptibility of diarrhoea producing gram negative enteric bacteria to sulfasalazine, 5-aminosalicylic acid, sulfapyridine and four quinolones. Brief report. APMIS. 1988 Jun;96(6):568-70. [Content Brief]
- [3]. Y L Hong, et al. Inhibition of recombinant Pneumocystis carinii dihydropteroate synthetase by sulfa drugs. Antimicrob Agents Chemother. 1995 Aug;39(8):1756-63. [Content Brief]
