117 Results for "

glp-1-receptor

" in MedChemExpress (MCE) Product Catalog:
Products (117)

117 Results for "glp-1-receptor" in MCE Product Catalog:

45
45 Publications Verification
Cat. No.: HY-P0264
CAS No.: 133514-43-9
Synonyms: Avexitide
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

Exendin(9-39) amide (Avexitide) is a glucagon-like peptide-1 (GLP-1) antagonist that competes with endogenous GLP-1 for binding to GLP-1 receptors, thereby antagonizing the effects of excess GLP-1 secretion. Exendin(9-39) amide can be used to study postoperative hypoglycemia (PBH) [1].
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42
42 Cited Publications
Cat. No.: HY-P0014
CAS No.: 204656-20-2
Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.
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25
25 Cited Publications
Cat. No.: HY-P1731C
Synonyms: LY3298176 sodium
Tirzepatide sodium (LY3298176 sodium) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Tirzepatide sodium exerts anti-apoptotic and pro-differentiation effects via the pAkt/CREB/BDNF cascade and miRNA in neurons; in the heart, it promotes BCAA catabolism and inhibits the mTOR pathway by mediating the dephosphorylation of BCKDHA; meanwhile, it effectively reduces insulin and leptin levels and suppresses inflammatory responses at the systemic level. Tirzepatide sodium can be used for research on myocardial infarction, colon cancer, diabetes, diabetic cognitive impairment, neurodegeneration, diabetes-related neuropathy, and obesity [1] .
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3
3 Cited Publications
Cat. No.: HY-P0119
CAS No.: 320367-13-3
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist. Lixisenatide inhibits the inflammatory response through down regulation of pro-inflammatory cytokines, and suppresses of the Akt-MEK1/2 signaling pathway. Lixisenatide can inhibit oxidative stress, mitochondrial dysfunction and apoptosis. Lixisenatide can be used for the researches of inflammation, metabolic disease, neurological disease and cardiovascular disease, such as rheumatoid arthritis, diabetes, Alzheimer's disease and atherosclerosis [1] .
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3
3 Cited Publications
Cat. No.: HY-P0119A
CAS No.: 1997361-87-1
Lixisenatide acetate is a glucagon-like peptide-1 (GLP-1) receptor agonist. Lixisenatide acetate inhibits the inflammatory response through down regulation of pro-inflammatory cytokines, and suppresses of the Akt-MEK1/2 signaling pathway. Lixisenatide acetate can inhibit oxidative stress, mitochondrial dysfunction and apoptosis. Lixisenatide acetate can be used for the researches of inflammation, metabolic disease, neurological disease and cardiovascular disease, such as rheumatoid arthritis, diabetes, Alzheimer's disease and atherosclerosis [1] .
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2
2 Cited Publications
Cat. No.: HY-112185
CAS No.: 2212020-52-3
Purity:  99.80%
Synonyms: LY3502970; glp-1 receptor agonist 1
Target:  

GCGR

Orforglipron (LY3502970) (Compound 67) is an orally active agonist for Glucagon-like peptide-1 receptor (GLP-1R), which exhibits potency in ameliorates the type 2 diabete [1].
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2
2 Cited Publications
Cat. No.: HY-112185A
CAS No.: 3008544-96-2
Purity:  99.71%
Synonyms: LY3502970 hemicalcium hydrate; glp-1 receptor agonist 1 hemicalcium hydrate
Target:  

GCGR

Orforglipron hemicalcium hydrate (LY3502970 hemicalcium hydrate; GLP-1 receptor agonist 1 hemicalcium hydrate) is the calcium salt hydrate form of Orforglipron (HY-112185). Orforglipron is an orally active agonist for Glucagon-like peptide-1 receptor (GLP-1R), which exhibits potency in ameliorating the type 2 diabete [1].
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2
2 Cited Publications
Cat. No.: HY-P700468
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: glp1R; glp-1-R; Glucagon Like Peptide 1 receptor; Seven Transmembrane Helix receptor; Glucagon-Like Peptide 1 receptor; glp1 receptor; glp-1R; glp-1; glp-1 receptor
Species:  
Human
Source:  
HEK293
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2
2 Cited Publications
Cat. No.: HY-P81160
Synonyms: Glucagon like peptide-1 receptor; glp 1 R; glp 1 receptor; glp 1R; glp1r; glp; glp1r; Glucagon like peptide 1 receptor; RATGL1RCP; Glip; MGC138331; glp-1-R; glp1R_HUMAN; Glucagon-like peptide 1 receptor; glp-1 receptor; glp-1-R; glp-1R; Precursor.

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-P0120
CAS No.: 923950-08-7
Synonyms: LY2189265
Target:  

GCGR

Research Areas:  

Metabolic Disease

Dulaglutide (LY2189265) is a glucagon-like peptide-1 (GLP-1) receptor agonist. Dulaglutide can be uesd for the research of type 2 diabetes (T2D) [1] .
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1
1 Cited Publications
Cat. No.: HY-103546
CAS No.: 1371569-69-5
Purity:  99.48%
Target:  

GCGR

Research Areas:  

Metabolic Disease

BETP is an agonist of glucagon-like peptide-1 (GLP-1) receptor, with EC50s of 0.66 and 0.755 μM for human and rat GLP-1 receptor, respectively.
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1
1 Cited Publications
Cat. No.: HY-P1145
CAS No.: 87805-34-3
Synonyms: glp-1 (1-37) human
Target:  

GCGR

Research Areas:  

Metabolic Disease

Glucagon-like peptide 1 (1-37), human is a highly potent agonist of the GLP-1 receptor.
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1
1 Cited Publications
Cat. No.: HY-N0630
CAS No.: 64421-28-9
Shanzhiside methy lester is isolated from lamiophlomis rotata. Shanzhiside methyl ester is a small molecule glucagon-like peptide-1 (GLP-1) receptor agonist and has the ability to induce anti-allodynic tolerance [1].
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1
1 Cited Publications
Cat. No.: HY-P1145A
Synonyms: Huglp-1 TFA
Target:  

GCGR

Research Areas:  

Metabolic Disease

Glucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor.
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1
1 Cited Publications
Cat. No.: HY-P2497
CAS No.: 196109-27-0
Target:  

GCGR

Research Areas:  

Neurological Disease

Exendin (5-39) is a potent glucagon-like peptide 1 (GLP-1) receptor antagonist. Exendin (5-39) improves memory impairment in β-amyloid protein-treated rats [1].
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1
1 Cited Publications
Cat. No.: HY-P72206
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: glp1R; glp-1-R; Glucagon Like Peptide 1 receptor; Seven Transmembrane Helix receptor; Glucagon-Like Peptide 1 receptor; glp1 receptor; glp-1R; glp-1; glp-1 receptor
Species:  
Mouse
Source:  
E. coli
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Cat. No.: HY-P4146
CAS No.: 2805997-46-8
Synonyms: BI 456906
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake [1].
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Cat. No.: HY-P3366
CAS No.: 2459531-73-6
Synonyms: XW003
Target:  

GCGR

Research Areas:  

Metabolic Disease

Ecnoglutide (XW003) is a long-acting, cAMP-biased glucagon-like peptide 1 (GLP-1) receptor agonist. Ecnoglutide can be used for research of T2DM and obesity [1] .
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Cat. No.: HY-P1141
CAS No.: 161748-29-4
Target:  

GCGR

Research Areas:  

Metabolic Disease

GLP-1(9-36)amide is a major metabolite of glucagon-like peptide-1-(7-36) amide formed by the enzyme dipeptidyl peptidase-4 (DPP-4). GLP-1(9-36)amide acts as an antagonist to the human pancreatic GLP-1 receptor [1] .
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Cat. No.: HY-156968
CAS No.: 3011682-51-9
Purity:  98.78%
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

GLP-1 receptor agonist 14 is a glucagon-like peptide-1 receptor (GLP-1 receptor) agonist. GLP-1 receptor agonist 14 can be used in research related to diabetes or other metabolic diseases [1].
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