1. GPCR/G Protein
  2. Glucagon Receptor

Dulaglutide (Synonyms: LY2189265)

Cat. No.: HY-P0120
Handling Instructions

Dulaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist.

For research use only. We do not sell to patients.
Dulaglutide Chemical Structure

Dulaglutide Chemical Structure

CAS No. : 923950-08-7

Size Price Stock
1 mg USD 336 Get quote
5 mg USD 1056 Get quote
10 mg USD 1680 Get quote

* Please select Quantity before adding items.

Other In-stock Forms of Dulaglutide:

Customer Review

Other Forms of Dulaglutide:

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Dulaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist.

IC50 & Target

GLP-1 receptor[1]

In Vivo

Dulaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist. No specific Dulaglutide-related cause of death is identified. Survival is numerically increased for both genders of animals in all Dulaglutide treatment groups and reaches statistical significance (P≤0.05) in the 0.5- and 5-mg/kg males and in the 0.05-, 0.5-, and 1.5-mg/kg females. Mean times to peak plasma concentration values of Dulaglutide are observed at 12 hours after dosing on day 1 and rang between 12 and 48 hours at week 52. The incidence of thyroid C-cell adenoma is significantly (P≤0.05) increased compare with controls in males and females at the Dulaglutide 0.5-, 1.5-, and 5-mg/kg doses[1].

Clinical Trial
References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 0.0168 mL 0.0838 mL 0.1676 mL
5 mM 0.0034 mL 0.0168 mL 0.0335 mL
10 mM 0.0017 mL 0.0084 mL 0.0168 mL
Please refer to the solubility information to select the appropriate solvent.
Animal Administration
[1]

The tumorigenic potential of Dulaglutide is evaluated in rats and transgenic mice. Rats are injected sc twice weekly for 93 weeks with Dulaglutide 0, 0.05, 0.5, 1.5, or 5 mg/kg corresponding to 0, 0.5, 7, 20, and 58 times, respectively. Transgenic mice are dosed sc twice weekly with Dulaglutide 0, 0.3, 1, or 3 mg/kg for 26 weeks[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
Molecular Weight

59669.81

Formula

C₂₆₄₆H₄₀₄₄N₇₀₄O₈₃₆S₁₈

CAS No.

923950-08-7

SMILES

[Dulaglutide]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Dulaglutide
Cat. No.:
HY-P0120
Quantity: