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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
44 Results for "
glutamine synthetase
" in MedChemExpress (MCE) Product Catalog:
Products (44)
44 Results for "glutamine synthetase" in MCE Product Catalog:
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Research Areas:
Glutamine synthetase is an enzyme that converts glutamate and ammonia into glutamine. Glutamine synthetase can inhibit angiogenesis in ocular and inflammatory skin diseases. Glutamine synthetase can also palmitoylate RHOJ, thereby inhibiting endothelial cell migration. Glutamine synthetase can be used in research on various diseases, including cardiovascular and cerebrovascular diseases and cancer .
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14 Publications Verification
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L-Methionine-DL-sulfoximine (MSX; MSO), a highly specific and irreversible inhibitor of Glutamine synthetase (GS), is also a potent convulsant which metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine has been employed to inhibit the Gln-dependent ammonia-stimulated neuronal toxicity in vitro, potentiating Gln deficit-dependent depression. L-Methionine-DL-sulfoximine tremendously increases the rate of release of fixed nitrogen in cyanobacteria. L-Methionine-DL-sulfoximine is a promising candidate for research in biofertilizers and convulsive seizures (CS) .
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5 Cited Publications
Cat. No.: HY-W017443
CAS No.: 5794-13-8
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2 Cited Publications
Cat. No.: HY-W338140
CAS No.: 1982-67-8
Synonyms: 2-Amino-4-(S-methylsulfonimidoyl)butanoic acid
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Methionine sulfoximine (2-Amino-4-(S-methylsulfonimidoyl)butanoic acid) is an irreversible inhibitor of glutamine synthetase with convulsive effects. Methionine sulfoximine is able to affect the metabolism of glutamate and glutamine, which may provide important insights in neurobiological research. Methionine sulfoximine has also been used to study mechanisms related to epilepsy and its inhibitory potential .
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1 Cited Publications
Cat. No.: HY-P990006
CAS No.: 2750005-84-4
Synonyms: TEV-48574; SAR-447189; TEV-574
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1 Cited Publications
Cat. No.: HY-N0667S2
CAS No.: 287484-32-6
Synonyms: (-)-Asparagine-15N2 monohydrate; Asn-15N2 monohydrate; Asparamide-15N2 monohydrate
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1 Cited Publications
Synonyms: Deamido nad sodium
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1 Cited Publications
Cat. No.: HY-N0667S5
CAS No.: 2483831-59-8
Synonyms: SF-1293 sodium
Bialaphos (SF-1293) sodium is a phosphinothricinylalanylalanine. Bialaphos sodium also acts as a precursor of herbicides and antibacterial agents. After entering bacterial or plant cells, Bialaphos sodium is converted into phosphinothricin, an inhibitor of glutamine synthetase .
Cat. No.: HY-W028047
CAS No.: 51070-56-5
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JFD01307SC is a glutamine synthetase inhibitor and anti-tuberculosis agent. JFD01307SC acts as a mimic of L-Glutamate and thus target enzymes involved in glutamine biosynthesis .
Cat. No.: HY-12688
CAS No.: 26647-82-5
Synonyms: (-)-Asparagine (Standard); Asn (Standard); Asparamide (Standard)
Cat. No.: HY-W017443S
CAS No.: 202406-87-9
Cat. No.: HY-N0667S3
CAS No.: 286460-82-0
Synonyms: (-)-Asparagine-13C4 monohydrate; Asn-13C4 monohydrate; Asparamide-13C4 monohydrate
Cat. No.: HY-W017443S1
CAS No.: 204451-47-8
Cat. No.: HY-W017443R
CAS No.: 5794-13-8
Category:
Cat. No.: HY-N0667S7
CAS No.: 781596-75-6
Synonyms: (-)-Asparagine-13C4,15N2; Asn-13C4,15N2; Asparamide-13C4,15N2
Cat. No.: HY-P2749A
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L-Glutamine Synthetase, Escherichia coli (EC 6.3.1.2) is an enzyme that plays an important role in nitrogen metabolism, catalyzing the condensation of glutamate and ammonia to produce glutamine. L-Glutamine Synthetase, Escherichia coli (EC 6.3.1.2) utilizes ammonia produced by nitrate reduction, amino acid degradation, and photorespiration.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
