3 Results for "

growth factor-induced cell proliferation

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "growth factor-induced cell proliferation" in MCE Product Catalog:

Cat. No.: HY-153227
CAS No.: 186611-58-5
Purity:  98.02%
Target:  

c-Met/HGFR

Research Areas:  

Cancer

SU 5616 is an indolinone compound that modulates tyrosine kinase signaling pathways to control aberrant cell proliferation .
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Cat. No.: HY-187640
CAS No.: 203051-01-8
Target:  

Phospholipase

Research Areas:  

Others

CRM-51005 is a phospholipase C (PLC)γ1 inhibitor with a bovine IC50 of 13.0 μg/mL. CRM-51005 inhibits PLCγ1 enzymatic activity and platelet-derived growth factor-induced phosphoinositide turnover. CRM-51005 acts as a cell growth inhibitor via suppression of PLC, phosphoinositide turnover, DNA synthesis, and cell proliferation .
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Cat. No.: HY-167262
CAS No.: 156691-86-0
Target:  

RAR/RXR

Research Areas:  

Metabolic Disease Cancer

AGN-191659 is an orally active RAR/RXR agonist with EC50 values of 11 nM, 23 nM, and 37 nM for RXRα, RARβ, and RARγ, respectively. AGN-191659 activates RXRα, RARβ and RARγ to induce gene transcription. AGN-191659 induces tissue transglutaminase activity, inhibits ornithine decarboxylase activity induced by tumor promoters, and suppresses chondrogenesis. AGN-191659 reverses basic fibroblast growth factor-induced endothelial cell proliferation. AGN-191659 induces hypertriglyceridemia in rat models. AGN-191659 inhibits total heparin-releasable lipase activity. AGN-191659 can be used in research related to promyelocytic leukemia and hypertriglyceridemia .
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