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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
hMAO-A
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "hMAO-A" in MCE Product Catalog:
3
Target:
Research Areas:
Moclobemide (Ro111163) is a brain-penetrant and reversible monoamine oxidase (MAO-A) inhibitor with an IC50 of 6.061 μM for hMAO-A .Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice.
Category:
Coumarins Phenols Polyphenols Phenylpropanoids Plants Umbelliferae Kleinia odora (Forssk.) DC.
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Cat. No.: HY-N6057
CAS No.: 70588-05-5
Category:
Seeds of Cassia tora Linn. Quinones other families Leguminosae Anthraquinones Phenols Polyphenols Plants
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Cat. No.: HY-114203
CAS No.: 88798-74-7
Synonyms: BE003
Category:
Target:
Cat. No.: HY-N4177
CAS No.: 24577-90-0
Synonyms: Rubrofusarin-6-β-gentiobioside
Category:
Seeds of Cassia tora Linn. other families Monophenols Leguminosae Metabolic Disease Phenols Plants Disease Research Fields
Target:
Cat. No.: HY-170938
Research Areas:
AChE-IN-82 (compound 49) is an acetylcholinesterase (AChE) inhibitor. AChE-IN-82 inhibits eeAChE, eqBChE, hMAO-A, hMAO-B, and BACE-1 with IC50s of 0.072, 9.81, 14.52, 0.024, 2.42 μM, respectively. AChE-IN-82 inhibits COX-1, COX-2 and 5-LOX with IC50s of 60.41, 0.187, 0.18 μM, respectively. AChE-IN-82 shows an excellent neuroprotective effect by significantly reducing oxidative stress induced by H2 O2 .
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hMAO-B-IN-4 (compound B10) is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value and a Ki value of 0.067 and 0.03 μM, respectively. hMAO-B-IN-4 inhibits hMAO-A with an IC50 value of 33.82 μM. hMAO-B-IN-4 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research .
Cat. No.: HY-N8200
CAS No.: 218155-40-9
Cat. No.: HY-N7603
CAS No.: 245724-07-6
Category:
Seeds of Cassia tora Linn. other families Monophenols Leguminosae Ketones, Aldehydes, Acids Phenols Plants
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Cat. No.: HY-W325160
CAS No.: 956-04-7
Research Areas:
4-Chlorochalcone (Compound 3) is a monoamine oxidase inhibitor (hMAO-B: IC50 = 0.082 μM, hMAO-A: IC50 = 9.95 μM). 4-Chlorochalcone also exhibits inhibitory activity against cholinesterase (AChE: IC50 = 2.79 μM). 4-Chlorochalcone is a chalcone derivative .
Cat. No.: HY-W207699
CAS No.: 27052-20-6
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
MAO-B-IN-46 (Compound 16) is a selective hMAO-B inhibitor (IC50: 26.8 nM), with weak activity against hMAO-A (IC50: 7.2054 μM). MAO-B-IN-46 (Compound 8) also acts as an α-amylase inhibitor (IC50: 19.46 μM). MAO-B-IN-46 exhibits certain neuroprotective effects and shows no significant toxicity to human gingival fibroblasts and SH-SY5Y cells. Additionally, MAO-B-IN-46 can scavenge DPPH and ABTS free radicals, with IC50 values of 17.86 μM and 17.71 μM, respectively. MAO-B-IN-46 can be used in the research of neurodegenerative diseases such as Parkinson's disease, diabetes, and diseases related to oxidative stress resistance .
Cat. No.: HY-157392
CAS No.: 1039315-88-2
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Research Areas:
hMAO-A-IN-1 (compound 8) is a potent hMAO-A inhibitor, with an IC50 of 90 nM. hMAO-A-IN-1 can be used for the research of anxiety and depression .
Cat. No.: HY-W035384
CAS No.: 1010879-39-6
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MAO-B ligand-1 is a MAO-B inhibitor, with IC50 values of 22.57 and 3.83 nM for hMAO-A and hMAO-B, respectively .
Cat. No.: HY-B0534S1
CAS No.: 2929883-33-8
Synonyms: Ro111163-d4
Cat. No.: HY-N7598
CAS No.: 54944-38-6
Category:
Seeds of Cassia tora Linn. Quinones other families Monophenols Leguminosae Anthraquinones Phenols Plants
Target:
Cat. No.: HY-B0534R
CAS No.: 71320-77-9
Synonyms: Ro111163 (Standard)
Target:
Research Areas:
Moclobemide (Standard) is the analytical standard of Moclobemide. This product is intended for research and analytical applications. Moclobemide (Ro111163) is a brain-penetrant and reversible monoamine oxidase (MAO-A) inhibitor with an IC50 of 6.061 μM for hMAO-A .Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice.
Cat. No.: HY-173395
Target:
Research Areas:
MAO-B-IN-43 (4) is a potent hMAO-B inhibitor and a weak GSK3β kinase inhibitor, with Ki values of 0.044 μM and 0.004 μM for hMAO-A and hMAO-B, respectively. MAO-B-IN-43 (4) can be used for the research of neurodegenerative disorder .
Cat. No.: HY-157087
Research Areas:
AChE/MAO-B-IN-4 (compound 4a) is a selective dual AChE and MAO-B inhibitor. AChE/MAO-B-IN-4 shows no significant inhibition activity against BChE and h-MAO-A. AChE/MAO-B-IN-4 can be used for the Alzheimer’s disease (AD) research .
Cat. No.: HY-B0534S
CAS No.: 2309010-25-9
Synonyms: Ro111163-d8
Cat. No.: HY-181110
Target:
Free Radical Scavengers Monoamine Oxidase Reactive Oxygen Species (ROS) Cholinesterase (ChE) Interleukin Related
Research Areas:
MAO-A-IN-4 is a highly selective and reversible inhibitor of monoamine oxidase A (MAO-A), with an IC50 of 0.06 μM against hMAO-A. MAO-A-IN-4 exhibits anti-inflammatory, antioxidant, neuroprotective, and antidepressant activities. MAO-A-IN-4 possesses favorable ADME properties and is suitable for research related to depression .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
