1666119-75-0
Chemical Structure
hMAO-B-IN-4
- CAS No.: 1666119-75-0
- Formula:C20H16O2S
- Molecular Weight:320.40
IUPAC Name: (E)-3-(4-(benzyloxy)phenyl)-1-(thiophen-2-yl)prop-2-en-1-one
InChIKey: MKSMRBDQELHEBO-JLHYYAGUSA-N
SMILES: O=C(C1=CC=CS1)/C=C/C2=CC=C(C=C2)OCC3=CC=CC=C3
Biological Activity: hMAO-B-IN-4 (compound B10) is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value and a Ki value of 0.067 and 0.03 μM, respectively. hMAO-B-IN-4 inhibits hMAO-A with an IC50 value of 33.82 μM. hMAO-B-IN-4 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research[1].
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hMAO-B-IN-4 | 99.70% | hMAO-B-IN-4 (compound B10) is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value and a Ki value of 0.067 and 0.03 μM, respectively. hMAO-B-IN-4 inhibits hMAO-A with an IC50 value of 33.82 μM. hMAO-B-IN-4 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research. | ||||||||||||||||||||
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Keywords
