10 Results for "

high-affinity IgE receptor

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "high-affinity IgE receptor" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99300
CAS No.: 1322627-61-1
Synonyms: QGE 031; Anti-IGHE Recombinant Antibody

Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

Ligelizumab (QGE 031) is a humanized high-affinity anti-immunoglobulin IgE monoclonal antibody. Ligelizumab selectively inhibits the binding of IgE to the high-affinity receptor FcεRI, while the inhibitory effect on the low-affinity receptor CD23 is weak. Ligelizumab can inhibit the activation of effector cells such as mast cells and Basophil, while reducing the production of IgE by B cells, and restoring the IFN-α production and regulatory T cell (Treg) induction function of plasmacytoid dendritic cells (pDC). Ligelizumab can be used in the study of allergic diseases (such as chronic spontaneous urticaria, allergic asthma) .
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Cat. No.: HY-124146
CAS No.: 1319738-39-0
Target:  

Syk

Research Areas:  

Inflammation/Immunology

BI1002494 is an orally active, potent, and selective spleen tyrosine kinase (SYK) inhibitor. BI 1002494 exhibits an IC50 of 115 nM in inhibiting high-affinity IgE receptor-mediated mast cell and basophil degranulation. BI1002494 can be utilized in immunology reesearch .
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Cat. No.: HY-P704589
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FCER1A; FcepsilonRI Alpha Chain; Prev. FCE1A; FcERI; FcepsilonRIalpha; Immunoglobulin E receptor, high-affinity, Of Mast Cells, Alpha Polypeptide; FCERIA; high affinity Immunoglobulin Epsilon receptor Alpha-Subunit; Fc Fragment Of IgE, high affinity I, receptor For; Alpha Polypeptide; Fc Of IgE, high affinity I, receptor For Alpha Polypeptide; high affinity Immunoglobulin Epsilon receptor Subunit Alpha; Fc IgE receptor, Alpha Polypeptide; Fc Fragment Of IgE receptor Ia; Fc Epsilon RI Alpha-Chain; IgE Fc receptor Subunit Alpha; Fc Epsilon receptor Ia; Fc-Epsilon RI-Alpha
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P705213
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCER1A; FcepsilonRI Alpha Chain; Prev. FCE1A; FcERI; FcepsilonRIalpha; Immunoglobulin E receptor, high-affinity, Of Mast Cells, Alpha Polypeptide; FCERIA; high affinity Immunoglobulin Epsilon receptor Alpha-Subunit; Fc Fragment Of IgE, high affinity I, receptor For; Alpha Polypeptide; Fc Of IgE, high affinity I, receptor For Alpha Polypeptide; high affinity Immunoglobulin Epsilon receptor Subunit Alpha; Fc IgE receptor, Alpha Polypeptide; Fc Fragment Of IgE receptor Ia; Fc Epsilon RI Alpha-Chain; IgE Fc receptor Subunit Alpha; Fc Epsilon receptor Ia; Fc-Epsilon RI-Alpha
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P703903
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCER1A; FcepsilonRI Alpha Chain; Prev. FCE1A; FcERI; FcepsilonRIalpha; Immunoglobulin E receptor, high-affinity, Of Mast Cells, Alpha Polypeptide; FCERIA; high affinity Immunoglobulin Epsilon receptor Alpha-Subunit; Fc Fragment Of IgE, high affinity I, Re
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P703902
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCER1A; FcepsilonRI Alpha Chain; Prev. FCE1A; FcERI; FcepsilonRIalpha; Immunoglobulin E receptor, high-affinity, Of Mast Cells, Alpha Polypeptide; FCERIA; high affinity Immunoglobulin Epsilon receptor Alpha-Subunit; Fc Fragment Of IgE, high affinity I, Re
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P72191
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCER1A; FcepsilonRI Alpha Chain; Prev. FCE1A; FcERI; FcepsilonRIalpha; Immunoglobulin E receptor, high-affinity, Of Mast Cells, Alpha Polypeptide; FCERIA; high affinity Immunoglobulin Epsilon receptor Alpha-Subunit; Fc Fragment Of IgE, high affinity I, Re
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P75212
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: FCER1A; FcepsilonRI Alpha Chain; Prev. FCE1A; FcERI; FcepsilonRIalpha; Immunoglobulin E receptor, high-affinity, Of Mast Cells, Alpha Polypeptide; FCERIA; high affinity Immunoglobulin Epsilon receptor Alpha-Subunit; Fc Fragment Of IgE, high affinity I, Re
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P811660
Synonyms: FCE1A, FCER1A, high affinity immunoglobulin epsilon receptor subunit alpha, Fc-epsilon RI-alpha, IgE Fc receptor subunit alpha, FcERI

Host:  

Rabbit

Application:  

WB, IHC-P, IF-Tissue, ELISA

Reactivity:  

Human

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Cat. No.: HY-P705217
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHE; Ig Epsilon Chain C Region; Immunoglobulin Heavy Constant Epsilon; Immunoglobulin Epsilon; Constant Region Of Heavy Chain Of IgE; IgE; Ig Epsilon Chain C Region ND
Species:  
Human
Source:  
HEK293
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