1319738-39-0

BI1002494 Chemical Structure
1319738-39-0

Chemical Structure

BI1002494

  • CAS No.: 1319738-39-0
  • Formula:C23H25N3O5
  • Molecular Weight:423.46

IUPAC Name: (R)-4-((R)-1-((7-(3,4,5-trimethoxyphenyl)-1,6-naphthyridin-5-yl)oxy)ethyl)pyrrolidin-2-one

InChIKey: BRYUNLVJDCMANZ-UKRRQHHQSA-N

SMILES: O=C1NC[C@@H](C1)[C@@H](C)OC2=C3C=CC=NC3=CC(C4=CC(OC)=C(C(OC)=C4)OC)=N2

Biological Activity: BI1002494 is an orally active, potent, and selective spleen tyrosine kinase (SYK) inhibitor. BI 1002494 exhibits an IC50 of 115 nM in inhibiting high-affinity IgE receptor-mediated mast cell and basophil degranulation. BI1002494 can be utilized in immunology reesearch[1].

Cat. No. Product Name Purity Description Pricing
HY-124146 		BI1002494 BI1002494 is an orally active, potent, and selective spleen tyrosine kinase (SYK) inhibitor. BI 1002494 exhibits an IC50 of 115 nM in inhibiting high-affinity IgE receptor-mediated mast cell and basophil degranulation. BI1002494 can be utilized in immunology reesearch.
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