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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
intrahepatic cholestasis
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "intrahepatic cholestasis" in MCE Product Catalog:
21
Category:
Human Gut Microbiota Metabolites Anti-aging Metabolic Disease Endogenous metabolite Disease Research Fields Steroids
Target:
1
Target:
Cat. No.: HY-16747
CAS No.: 228113-66-4
Synonyms: SHP625 chloride; LUM001 chloride; Lopixibat chloride
Research Areas:
Maralixibat (SHP625) chloride is an orally active ileal bile acid transporter (IBAT) inhibitor. Maralixibat chloride can be used for the research of rare cholestatic liver diseases including Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC) and biliary atresia .
Target:
Cat. No.: HY-W353102
CAS No.: 1806-98-0
Category:
Monophenols Metabolic Disease Phenols Endogenous metabolite Disease Research Fields Endocrinology Steroids
Target:
Cat. No.: HY-168523
CAS No.: 259528-99-9
Research Areas:
S1647 is a ASBT and SOAT dual inhibitor. S1647 can be used in the study of intrahepatic cholestasis, cholestatic pruritus, and obstipation .
Cat. No.: HY-P703251
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ABCB11; SPGP; Prev. BSEP; Progressive Familial intrahepatic cholestasis 2; Prev. PFIC2; ATP-Binding Cassette Sub-Family B Member 11; Bile Salt Export Pump; ABC Member 16, MDR/TAP Subfamily; PFIC-2; Uncharacterized Protein ABCB11; ABC16; Sister P-Glycoprot
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-E72116
Target:
Research Areas:
Human UGT2B4 is a UDP-glucuronosyltransferase. UGT2B4 catalyzes the glucuronidation of bile acids, Carvedilol (HY-B0006) and 6-hydroxylated bile acids to form glucuronide derivatives. UGT2B4 participates in the inactivation of endogenous and exogenous substances, including catechol estrogens, C19 steroids, phenols and monoterpenoids. Human UGT2B4 can be used in the research of hypertension, angina pectoris, chronic heart failure and intrahepatic cholestasis .
Cat. No.: HY-P1654A
CAS No.: 3107375-56-1
Cat. No.: HY-D3304
CAS No.: 2770684-20-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
