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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
kidney transplantation
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "kidney transplantation" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-P1237
CAS No.: 127869-51-6
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Cardiovascular Disease Neurological Disease Metabolic Disease
3
3 Cited Publications
Cat. No.: HY-P1237A
CAS No.: 1966153-17-2
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease
1
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Synonyms: BMS 224818; LEA 29Y
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Cat. No.: HY-P990083
CAS No.: 2628092-47-5
Synonyms: AT-1501
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Synonyms: ANG-3777
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Terevalefim (ANG-3777), an hepatocyte growth factor (HGF) mimetic, selectively activates the c-Met receptor .
Cat. No.: HY-P99152
CAS No.: 140608-64-6
Synonyms: Muromanab-CD3
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Cat. No.: HY-N3181
CAS No.: 10391-09-0
Cat. No.: HY-P991557
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Cat. No.: HY-P990083A
CAS No.: 2628092-47-5
Synonyms: AT-1501 (powder)
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Cat. No.: HY-P12125
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Cat. No.: HY-115464
CAS No.: 150661-91-9
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NC1153 is a Mannich base with the activity to block IL-2-induced JAK3 activation and its downstream substrate STAT5a/b. NC1153 effectively prolongs the survival of kidney transplants in MHC/non-MHC mismatched rats. NC1153 promotes long-term graft survival and includes multiple toxicity protection for recipients. NC1153 combined with cyclosporine A (CsA) can synergistically prolong graft survival without producing nephrotoxicity, myelotoxicity or lipotoxicity .
Cat. No.: HY-10540
CAS No.: 908351-31-5
Synonyms: AEB071 acetate
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Sotrastaurin (AEB071) acetate is a selective, orally active PKC inhibitor. Sotrastaurin acetate inactivates NF-κB by inhibiting PKC α, β, θ, γ subtypes, thereby reducing the transcription levels of immune response-related genes. Sotrastaurin acetate effectively inhibits alloreactive T cell proliferation, conventional T cell activation, as well as the production of pro-inflammatory cytokines and B lymphocytes. Sotrastaurin acetate also maintains the functional and phenotypic stability of regulatory T cells, enhances Foxp3 expression and restores the balance of helper T lymphocytes. Sotrastaurin acetate can prolong the survival time of allografts, and alleviate inflammatory responses and myasthenic symptoms by reducing anti-AChR antibody levels. Sotrastaurin acetate is widely used in studies related to kidney transplantation, psoriasis and myasthenia gravis .
Cat. No.: HY-185359
CAS No.: 2509539-79-9
HDAC6-IN-78 (Example 48) is a selective HDAC6 inhibitor with an IC50 of 24 nM. HDAC6-IN-78 shows no activity against other HDAC isoforms .
Cat. No.: HY-P991921
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
