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lectin-like oxidized LDL receptor-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	LOX-1 (1)
By Research Areas:	Cardiovascular Disease (1)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Targets Recommended: LOX-1 C-type Lectin-like Receptors (CTLRs) CX3CR1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-23999

BI-0115 2 Publications Verification	LOX-1	Cardiovascular Disease
BI-0115 is a selective inhibitor of LOX-1 (IC₅₀=5.4 μM) that blocks cellular uptake of oxLDL. BI-0115 binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain .

Species:	Human (1) Rat (2) Cynomolgus (1)
Tag:	His (3) Fc (1)
Source:	HEK293 (4)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71180

	LOX-1/OLR1 Protein, Human (HEK293, His) oxidized Low-Density Lipoprotein receptor 1; Ox-LDL receptor 1; C-Type lectin Domain Family 8 Member A; lectin-like oxidized LDL receptor 1; LOX-1; lectin-like oxLDL receptor 1; hLOX-1; lectin-Type oxidized LDL receptor 1; OLR1; CLEC8A; LOX1	Human	HEK293
	The OLR1 protein is a receptor on vascular endothelial cells that plays a key role in the recognition, internalization, and degradation of oxidatively modified low-density lipoprotein (oxLDL). As a marker of atherosclerosis, oxLDL induces activation of vascular endothelial cells, leading to proinflammatory responses, oxidative conditions, and apoptosis. OLR1 Protein, Human (HEK293, His) is the recombinant human-derived OLR1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P73835

	LOX-1/OLR1 Protein, Rat (HEK293, His) oxidized low-density lipoprotein receptor 1; LOX-1; OLR1; CLEC8A	Rat	HEK293
	The LOX-1/OLR1 protein plays an important role as a receptor that recognizes, internalizes, and degrades oxidatively modified low-density lipoprotein (oxLDL), a marker of atherosclerosis, in vascular endothelial cells. OxLDL induces endothelial dysfunction, triggering pro-inflammatory responses, oxidative conditions, and apoptosis. LOX-1/OLR1 Protein, Rat (HEK293, His) is the recombinant rat-derived LOX-1/OLR1 protein, expressed by HEK293 , with N-His labeled tag.

HY-P76474

	LOX-1/OLR1 Protein, Cynomolgus (HEK293, His) oxidized low-density lipoprotein receptor 1; LOX-1; OLR1; CLEC8A	Cynomolgus	HEK293
	OLR1 is a type II membrane glycoprotein belonging to C-type lectin family with a short N-terminal cytoplasmic tail and a long C-terminal extracellular domain. OLR1 binds ox-LDL, delipidated, and solubilized ox-LDL. LOX-1/OLR1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived LOX-1/OLR1 protein, expressed by HEK293 , with N-His labeled tag.

HY-P73836

	LOX-1/OLR1 Protein, Rat (HEK293, Fc) oxidized low-density lipoprotein receptor 1; LOX-1; OLR1; CLEC8A	Rat	HEK293
	The LOX-1/OLR1 protein plays an important role as a receptor that recognizes, internalizes, and degrades oxidatively modified low-density lipoprotein (oxLDL), a marker of atherosclerosis, in vascular endothelial cells. OxLDL induces endothelial dysfunction, triggering pro-inflammatory responses, oxidative conditions, and apoptosis. LOX-1/OLR1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived LOX-1/OLR1 protein, expressed by HEK293 , with N-hFc labeled tag.

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Host:	Rabbit (2)
Reactivity:	Human (2) Mouse (1) Rat (1) Rabbit (1)
Application:	IHC-P (2) ICC/IF (1) WB (2) FC (1)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Polyclonal (1) polyclonal (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81172

	LOX 1 Antibody lectin-type oxidized LDL receptor 1; OLR1; lectin-like low density lipoprotein receptor-1; oxidized low-density lipoprotein receptor 1; Ox-LDL receptor 1; lectin-like oxidized LDL receptor 1; lectin-like oxLDL receptor 1; LOX-1; BLOX1; Contains: oxidized low-density lipoprotein receptor 1, soluble form A; oxidized low-density lipoprotein receptor 1, soluble form B; OLR1_HUMAN.	WB, IHC-P, ICC/IF, FC	Human, Rat, Rabbit
	LOX 1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to LOX 1.

HY-P810504

	LOX1 Antibody CLEC8A, LOX1, OLR1, oxidized low-density lipoprotein receptor 1, Ox-LDL receptor 1, C-type lectin domain family 8 member A, lectin-like oxidized LDL receptor 1, lectin-type oxidized LDL receptor 1, LOX-1, lectin-like oxLDL receptor 1, hLOX-1	WB, IHC-P	Human, Mouse
	LOX1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to LOX1.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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