4929-23-1
4929-23-1
Chemical Structure
BI-0115
- CAS No.: 4929-23-1
- Formula:C15H14ClN3O
- Molecular Weight:287.74
IUPAC Name: 9-chloro-5-propyl-5,11-dihydro-6H-benzo[e]pyrido[3,2-b][1,4]diazepin-6-one
InChIKey: QTCZUCSALXBZQR-UHFFFAOYSA-N
SMILES: O=C1N(CCC)C2=CC=CN=C2NC3=CC(Cl)=CC=C13
Biological Activity: BI-0115 is a selective inhibitor of LOX-1 (IC50=5.4 μM) that blocks cellular uptake of oxLDL. BI-0115 binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain[1].
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BI-0115 | 99.72% | BI-0115 is a selective inhibitor of LOX-1 (IC50=5.4 μM) that blocks cellular uptake of oxLDL. BI-0115 binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.63
HY-167672Propizepine -
Similarity Score 0.63
HY-W156961LS-75 -
Similarity Score 0.58
![8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one (Standard) Chemical Structure](//file.medchemexpress.com/product_pic/hy-w129146r.gif)
HY-W129146R8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one (Standard) -
Similarity Score 0.57
HY-12391ADibenzepine hydrochloride -
Similarity Score 0.54
HY-18633MDK83190 -
Similarity Score 0.53
HY-42476Tolvaptan Impurity -
Similarity Score 0.53
HY-12388AN-Desmethyl clomipramine hydrochloride -
Similarity Score 0.53
HY-12388N-Desmethyl clomipramine -
Similarity Score 0.53
HY-W750632Clobazam impurity 4 -
Explore the MedChemAI to find more analogs
![8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one (Standard) Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w129146r.gif)
