2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. N-Desmethyl Clomipramine hydrochloride

N-Desmethyl Clomipramine hydrochloride  (Synonyms: Desmethylclomipramine hydrochloride)

Cat. No.: HY-12388A Purity: 99.73%
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N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine. Clomipramine is a tricyclic antidepressant.

For research use only. We do not sell to patients.

N-Desmethyl Clomipramine hydrochloride Chemical Structure

N-Desmethyl Clomipramine hydrochloride Chemical Structure

CAS No. : 29854-14-6

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5 mg USD 70 In-stock
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50 mg USD 315 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of N-Desmethyl Clomipramine hydrochloride:

N-Desmethyl Clomipramine hydrochloride Related Antibodies

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Description

N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine. Clomipramine is a tricyclic antidepressant[1][2].

Molecular Weight

337.29

Formula

C18H22Cl2N2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CNCCCN1C2=CC(Cl)=CC=C2CCC3=CC=CC=C31.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (74.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9648 mL 14.8240 mL 29.6481 mL
5 mM 0.5930 mL 2.9648 mL 5.9296 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9648 mL 14.8240 mL 29.6481 mL 74.1202 mL
5 mM 0.5930 mL 2.9648 mL 5.9296 mL 14.8240 mL
10 mM 0.2965 mL 1.4824 mL 2.9648 mL 7.4120 mL
15 mM 0.1977 mL 0.9883 mL 1.9765 mL 4.9413 mL
20 mM 0.1482 mL 0.7412 mL 1.4824 mL 3.7060 mL
25 mM 0.1186 mL 0.5930 mL 1.1859 mL 2.9648 mL
30 mM 0.0988 mL 0.4941 mL 0.9883 mL 2.4707 mL
40 mM 0.0741 mL 0.3706 mL 0.7412 mL 1.8530 mL
50 mM 0.0593 mL 0.2965 mL 0.5930 mL 1.4824 mL
60 mM 0.0494 mL 0.2471 mL 0.4941 mL 1.2353 mL
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N-Desmethyl Clomipramine hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Desmethyl Clomipramine29854-14-6DesmethylclomipramineDrug MetaboliteplasmaN-desmethylmetaboliteClomipraminetricyclicantidepressantInhibitorinhibitorinhibit

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