N-Desmethyl clomipramine hydrochloride
Based on 1 Customer Validation
N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine. Clomipramine is a tricyclic antidepressant.
For research use only. We do not sell to patients.
- Purity: 99.78%
- CAS No.: 29854-14-6
- Formula: C18H22Cl2N2
- Molecular Weight:337.29
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 29854-14-6
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Appearance Solid
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Molecular Weight 337.29
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Formula C18H22Cl2N2
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Color White to pink
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SMILES
CNCCCN1C2=CC(Cl)=CC=C2CCC3=CC=CC=C31.[H]Cl
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Synonyms
Desmethylclomipramine hydrochloride; Norclomipramine hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 25 mg/mL (74.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (459 KB)
- English - EN (459 KB)
- Français - FR (459 KB)
- Deutsch - DE (459 KB)
- Norwegian - NO (459 KB)
- Español - ES (459 KB)
- Swedish - SV (459 KB)
- Italian - IT (459 KB)
- Korean - KR (459 KB)
- Portuguese - PT (459 KB)
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Handling Instructions (2659 KB)
References
[1]. Sioufi A, et al. Simultaneous determination of clomipramine and its N-desmethyl metabolite in human whole blood by capillary gas chromatography with mass-selective detection. J Chromatogr. 1988 Jun 24;428(1):71-80. [Content Brief]
[2]. Härtter S, et al. Non-competitive inhibition of clomipramine N-demethylation by fluvoxamine. Psychopharmacology (Berl). 1995 Jan;117(2):149-53. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9648 mL | 14.8240 mL | 29.6481 mL | 74.1202 mL |
| 5 mM | 0.5930 mL | 2.9648 mL | 5.9296 mL | 14.8240 mL | |
| 10 mM | 0.2965 mL | 1.4824 mL | 2.9648 mL | 7.4120 mL | |
| 15 mM | 0.1977 mL | 0.9883 mL | 1.9765 mL | 4.9413 mL | |
| 20 mM | 0.1482 mL | 0.7412 mL | 1.4824 mL | 3.7060 mL | |
| 25 mM | 0.1186 mL | 0.5930 mL | 1.1859 mL | 2.9648 mL | |
| 30 mM | 0.0988 mL | 0.4941 mL | 0.9883 mL | 2.4707 mL | |
| 40 mM | 0.0741 mL | 0.3706 mL | 0.7412 mL | 1.8530 mL | |
| 50 mM | 0.0593 mL | 0.2965 mL | 0.5930 mL | 1.4824 mL | |
| 60 mM | 0.0494 mL | 0.2471 mL | 0.4941 mL | 1.2353 mL |
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