LS-75
Based on 1 Customer Validation
LS-75 is a PARP-1 inhibitor with blood-brain permeability and IC50 value of 18 μM. LS-75 has neuroprotective activity.
For research use only. We do not sell to patients.
- Purity: 99.31%
- CAS No.: 885-70-1
- Formula: C12H9N3O
- Molecular Weight:211.22
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Chemical Information
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CAS No. 885-70-1
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Appearance Solid
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Molecular Weight 211.22
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Formula C12H9N3O
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Color White to light yellow
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SMILES
O=C1C2=CC=CC=C2NC=3N=CC=CC3N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 33.33 mg/mL (157.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7344 mL | 23.6720 mL | 47.3440 mL | 118.3600 mL |
| 5 mM | 0.9469 mL | 4.7344 mL | 9.4688 mL | 23.6720 mL | |
| 10 mM | 0.4734 mL | 2.3672 mL | 4.7344 mL | 11.8360 mL | |
| 15 mM | 0.3156 mL | 1.5781 mL | 3.1563 mL | 7.8907 mL | |
| 20 mM | 0.2367 mL | 1.1836 mL | 2.3672 mL | 5.9180 mL | |
| 25 mM | 0.1894 mL | 0.9469 mL | 1.8938 mL | 4.7344 mL | |
| 30 mM | 0.1578 mL | 0.7891 mL | 1.5781 mL | 3.9453 mL | |
| 40 mM | 0.1184 mL | 0.5918 mL | 1.1836 mL | 2.9590 mL | |
| 50 mM | 0.0947 mL | 0.4734 mL | 0.9469 mL | 2.3672 mL | |
| 60 mM | 0.0789 mL | 0.3945 mL | 0.7891 mL | 1.9727 mL | |
| 80 mM | 0.0592 mL | 0.2959 mL | 0.5918 mL | 1.4795 mL | |
| 100 mM | 0.0473 mL | 0.2367 mL | 0.4734 mL | 1.1836 mL |