![[3-Methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] Kinase](https://file.medchemexpress.com/product_pic/hy-e72091.gif "Click to View [3-Methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] Kinase Product Detail")
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
leucine catabolism
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "leucine catabolism" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-N11200
CAS No.: 99159-87-2
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Target:
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Isovaleryl-CoA sodium is a branched-chain acyl-CoA and an inhibitor of succinate-CoA ligase (SCL), with an IC50 of 273 μM in rat liver mitochondria .
Cat. No.: HY-113278S
Research Areas:
Leucyl-phenylalanine- 13C6, 15N TFA is the 13C, 15N-labeled Leucyl-phenylalanine (HY-113278). Leucyl-phenylalanine is a linear dipeptide composed of L-leucine and L-phenylalanine, and also serves as a cyclization substrate. Leucyl-phenylalanine is an incomplete degradation product generated during protein breakdown or catabolism. Leucyl-phenylalanine undergoes heat-induced solid-state cyclization via an autocatalytic mechanism to form its cyclic diketopiperazine analog .
Cat. No.: HY-W654243
Cat. No.: HY-N11200R
CAS No.: 99159-87-2
Category:
Cat. No.: HY-113232S
CAS No.: 1276197-31-9
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3-Methylcrotonylglycine-d2 is the deuterated-labeled 3-Methylcrotonylglycine (HY-113232). 3-Methylcrotonylglycine is an organic acid conjugate associated with leucine catabolism that inhibits respiratory chain complex II-III, mitochondrial creatine kinase, and synaptic membrane Na +, K +-ATPase. 3-Methylcrotonylglycine increases reactive oxygen species levels to mediate oxidative damage, while inhibiting mitochondrial electron transport, reducing tricarboxylic acid cycle flux, and interfering with intracellular energy transport and neuronal ion homeostasis. 3-Methylcrotonylglycine is a neurotoxic metabolite that accumulates in the metabolic pathway of 3-methylcrotonyl-CoA carboxylase deficiency. 3-Methylcrotonylglycine can be used in studies related to 3-methylcrotonyl-CoA carboxylase deficiency .
Cat. No.: HY-W101499
CAS No.: 3062-14-4
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L-a-Aspartyl-L-leucine is a dipeptide composed of aspartate and leucine. It is an incomplete breakdown product of protein digestion or protein catabolism.
Cat. No.: HY-E72091
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Research Areas:
[3-Methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase (EC 2.7.11.4) is an ATP-dependent serine/threonine protein kinase that inactivates the branched-chain α-keto acid dehydrogenase complex (BCKDH) by phosphorylating its E1α subunit, thereby inhibiting the catabolism of leucine, isoleucine, and valine.
Cat. No.: HY-113278R
CAS No.: 3063-05-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
