Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
leukotriene C4
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "leukotriene C4" in MCE Product Catalog:
Category:
Infection Natural Products Immune System Disorder Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Inflammation/Immunology Cardiovascular System Disorder
Target:
2
2 Cited Publications
Target:
Research Areas:
TK05 is a potent and selective inhibitor of leukotriene C4 synthase (LTC4S) with an IC50 of 95 nM .
1
1 Cited Publications
Target:
Research Areas:
AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD9898 mitigates the GABA binding and hepatic toxicity signal. AZD9898 has the potential to treat asthma .
1
1 Cited Publications
Cat. No.: HY-P700729
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GGT1; GGT 1; Prev. GGT; Gamma-Glutamyltranspeptidase; D22S732; Gamma-Glutamyltransferase; D22S672; Glutathione Hydrolase; CD224; CD224 Antigen; Glutathione Hydrolase 1 Proenzyme; GGT1 Protein; Gamma-Glutamyltranspeptidase 1; GGTD; leukotriene-C4 Hydrolase
Species:
Human
Source:
HEK293
Synonyms: (S)-(-)-Verapamil hydrochloride
Research Areas:
(S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells .
Synonyms: FPL 59002
Research Areas:
Nedocromil suppresses the action or formation of multiple mediators, including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).
Cat. No.: HY-P10856
CAS No.: 3085809-95-3
Target:
Research Areas:
Cat. No.: HY-107609
CAS No.: 154978-38-8
Target:
Research Areas:
BAY-u 9773 is a selective cysteinyl-leukotriene receptor antagonist. BAY-u 9773 competitively antagonizes cysteinyl-leukotriene-induced contractions at typical and atypical cysteinyl-leukotriene receptors with comparable activity. BAY-u 9773 can be used for the research of trichomoniasis .
Cat. No.: HY-134092
CAS No.: 131391-65-6
Synonyms: N-Methyl-LTC4
Target:
Research Areas:
N-Methyl Leukotriene C4 (N-Methyl-LTC4) is a non-metabolizable LTC4 analog and a selective cysteinyl leukotriene receptor 2 (CysLT2) agonist, with an EC50 of 46.1 nM for mouse CysLT2 and an EC50 value of 122.3 nM for human CysLT2. N-Methyl Leukotriene C4 shows low potency against CysLT1. N-Methyl Leukotriene C4 activates human and mouse CysLT2 receptors, triggering calcium signaling, β-arrestin-2 binding to phosphorylated receptors, vascular leakage, hypotension, tachycardia, contraction of guinea pig ileum and trachea, mild bronchoconstriction, as well as hypertension associated with peripheral vasoconstriction. N-Methyl Leukotriene C4 can be used in research on asthma, rhinitis, sinusitis, cerebral inflammation and edema, pulmonary arterial hypertension, and cardiovascular diseases .
Cat. No.: HY-126716
CAS No.: 73958-10-8
Target:
Research Areas:
Leukotriene C4 methyl ester is a methyl ester of leukotriene C4. Leukotriene C4 methyl ester can be used for the research of psoriasis .
Cat. No.: HY-130429
CAS No.: 75290-60-7
Synonyms: Eoxin C4
Target:
Cat. No.: HY-113460
CAS No.: 74841-69-3
Category:
Target:
Synonyms: BAY X 1005; DG-031
Target:
Research Areas:
Veliflapon (BAY X 1005; DG-031) is an orally active and selective 5-lipoxygenase activating protein (FLAP) inhibitor . Veliflapon inhibits the synthesis of the leukotrienes B4 and C4 .
Cat. No.: HY-168498
CAS No.: 2761767-18-2
Target:
Research Areas:
GJG057 is a selective, orally active inhibitor for leukotriene C4 synthase (LTC4S) with an IC50 of 44 nM. GJG057 exhibits anti-inflammatory activity in mouse skin inflammation model and mouse asthma model .
Cat. No.: HY-126716S
Cat. No.: HY-U00364
CAS No.: 104961-19-5
Research Areas:
CI-949 is an allergic mediator release inhibitor, which inhibits histamine, leukotriene C4/D4 (LTC4/LTD4), and thromboxane B2 (TXB2) release with IC50s of 11.4 μM, 0.5 μM and 0.1 μM, respectively.
Cat. No.: HY-113693
CAS No.: 103176-67-6
Target:
Research Areas:
ONO-RS-347 is an orally active and potent antagonist of leukotriene C4 and D4. ONO-RS-347 inhibits LTD4-induced bronchoconstriction in guinea pigs. ONO-RS-347 is promising for research of allergic asthma and other immediate hypersensitivty diseases .
Cat. No.: HY-103158
CAS No.: 134470-38-5
Target:
Research Areas:
BW B70C is a potent, selective and orally activearachidonic acid 5-lipoxygenase inhibitor. BW B70C inhibits both acute and allergic bronchoconstriction and late-phase eosinophil accumulation subsequent to allergen inhalation in guinea-pigs. BW B70C prevents leukotriene C4 synthesis and reduces leucocyte migration to the airways lumen as well as albumin microvascular leakage. BW B70C has the potential for the research of anti-asthma agent .
Cat. No.: HY-16344
CAS No.: 69049-74-7
Synonyms: FPL 59002KP; Nedocromil disodium salt
Research Areas:
Nedocromil sodium suppresses the action or formation of multiple mediators, including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
