72025-60-6
Chemical Structure
Leukotriene C4
- CAS No.: 72025-60-6
- Formula:C30H47N3O9S
- Molecular Weight:625.77
IUPAC Name: (5S,6R,7E,9E,11Z,14Z)-6-(((R)-2-((S)-4-amino-4-carboxybutanamido)-3-((carboxymethyl)amino)-3-oxopropyl)thio)-5-hydroxyicosa-7,9,11,14-tetraenoic acid
InChIKey: GWNVDXQDILPJIG-NXOLIXFESA-N
SMILES: OC(CCC[C@H](O)[C@@H](/C=C/C=C/C=C\C/C=C\CCCCC)SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@H](N)C(O)=O)=O)=O
Biological Activity:
Leukotriene C4 is a eicosanoid lipid mediator and produced by immune cells during type 2 inflammation. Leukotriene C4 can mediate inflammation,allergy, bronchoconstriction, and vascular leakage[1][2].
The product specifications provided below refer solely to the active content of Leukotriene C4.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Leukotriene C4 | 95.75% | Leukotriene C4 is a eicosanoid lipid mediator and produced by immune cells during type 2 inflammation. Leukotriene C4 can mediate inflammation,allergy, bronchoconstriction, and vascular leakage. The product specifications provided below refer solely to the active content of Leukotriene C4. |
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Leukotriene C4-d5 | 97.9% | Leukotriene C4-d5 is the deuterium labeled Leukotriene C4. Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. The product specifications provided below refer solely to the active content of Leukotriene C4-d5. |
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Similarity Score 1.00
HY-11346011-trans-Leukotriene C4 -
Similarity Score 0.95
HY-13042914,15-Leukotriene C4 -
Similarity Score 0.93
HY-126716Leukotriene C4 methyl ester -
Similarity Score 0.93
HY-134092N-Methyl Leukotriene C4 -
Similarity Score 0.87
HY-130440Leukotriene F4 -
Similarity Score 0.82
HY-125408Maresin conjugates in tissue regeneration 1 -
Similarity Score 0.82
HY-125445PCTR1 -
Similarity Score 0.79
HY-113456SLeukotriene D4-d5 -
Similarity Score 0.78
HY-113456Leukotriene D4 -
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References
- [1]. Voisin T, et, al. The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2022087118. [Content Brief]
- [2]. Dvash E, et, al. Leukotriene C4 is the major trigger of stress-induced oxidative DNA damage. Nat Commun. 2015 Dec 11;6:10112. [Content Brief]
