72025-60-6
72025-60-6
Chemical Structure
Leukotriene C4
- CAS No.: 72025-60-6
- Formula:C30H47N3O9S
- Molecular Weight:625.77
IUPAC Name: (5S,6R,7E,9E,11Z,14Z)-6-(((R)-2-((S)-4-amino-4-carboxybutanamido)-3-((carboxymethyl)amino)-3-oxopropyl)thio)-5-hydroxyicosa-7,9,11,14-tetraenoic acid
InChIKey: GWNVDXQDILPJIG-NXOLIXFESA-N
SMILES: OC(CCC[C@H](O)[C@@H](/C=C/C=C/C=C\C/C=C\CCCCC)SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@H](N)C(O)=O)=O)=O
Biological Activity: Leukotriene C4 is a eicosanoid lipid mediator and produced by immune cells during type 2 inflammation. Leukotriene C4 can mediate inflammation,allergy, bronchoconstriction, and vascular leakage[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Leukotriene C4 | 95.8% | Leukotriene C4 is a eicosanoid lipid mediator and produced by immune cells during type 2 inflammation. Leukotriene C4 can mediate inflammation,allergy, bronchoconstriction, and vascular leakage. | ||||||||||||||||||||
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Leukotriene C4-d5 | 97.9% | Leukotriene C4-d5 is the deuterium labeled Leukotriene C4. Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. | ||||||||||||||||||||
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References
- [1]. Voisin T, et, al. The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2022087118. [Content Brief]
- [2]. Dvash E, et, al. Leukotriene C4 is the major trigger of stress-induced oxidative DNA damage. Nat Commun. 2015 Dec 11;6:10112. [Content Brief]
