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  4. Leukotriene C4

Leukotriene C4 is a eicosanoid lipid mediator and produced by immune cells during type 2 inflammation. Leukotriene C4 can mediate inflammation,allergy, bronchoconstriction, and vascular leakage.

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Leukotriene C4 Chemical Structure

Leukotriene C4 Chemical Structure

CAS No. : 72025-60-6

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25 μg (159.8 µM * 250 μL in Ethanol) USD 420 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Leukotriene C4 is a eicosanoid lipid mediator and produced by immune cells during type 2 inflammation. Leukotriene C4 can mediate inflammation,allergy, bronchoconstriction, and vascular leakage[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. Leukotriene C4 is produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets. Leukotriene C4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

625.77

Formula

C30H47N3O9S

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

OC(CCC[C@H](O)[C@@H](/C=C/C=C/C=C\C/C=C\CCCCC)SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@H](N)C(O)=O)=O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

Purity & Documentation

Purity: ≥97.0%

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Leukotriene C4
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HY-113446
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