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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
mammalian DNA polymerases
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "mammalian DNA polymerases" in MCE Product Catalog:
Cat. No.: HY-N7066
CAS No.: 91296-86-5
Synonyms: A-56619 hydrochloride
Target:
Research Areas:
Difloxacin hydrochloride (A-56619 hydrochloride) is an orally active bactericidal agent. Difloxacin hydrochloride inhibits bacterial DNA gyrase. Difloxacin hydrochloride exhibits concentration-dependent bactericidal activity. Difloxacin hydrochloride shows strong in vitro activity against a variety of Gram-positive and Gram-negative bacteria. Difloxacin hydrochloride can be used in research related to colibacillosis and *Staphylococcus aureus* infections .
Cat. No.: HY-131605B
Synonyms: GCV-TP disodium
Target:
Ganciclovir triphosphate disodium solution (100 mM ± 3 mM) (GCV-TP disodium) is a competitive DNA polymerase inhibitor and a metabolite of Ganciclovir (HY-13637). Ganciclovir triphosphate disodium solution (100 mM ± 3 mM) can replace Guanine-5'-triphosphate to terminate DNA chain extension, and mimics dGTP (HY-138616) to compete with mammalian DNA polymerases. Ganciclovir triphosphate disodium solution (100 mM ± 3 mM) can be used in research related to HSV infection, retinoblastoma, glioblastoma and colorectal cancer .
Cat. No.: HY-131605
CAS No.: 86761-38-8
Synonyms: GCV-TP
Target:
Research Areas:
Ganciclovir triphosphate (GCV-TP) is a competitive DNA polymerase inhibitor and a metabolite of Ganciclovir (HY-13637). Ganciclovir triphosphate can replace Guanine-5'-triphosphate to terminate DNA chain extension, and mimics dGTP (HY-138616) to compete with mammalian DNA polymerases. Ganciclovir triphosphate can be used in research related to HSV infection, retinoblastoma, glioblastoma and colorectal cancer .
Cat. No.: HY-170547
CAS No.: 2701561-91-1
Target:
Research Areas:
DNA polymerase-IN-6 is an antiviral agent and a DNA polymerase inhibitor. DNA polymerase-IN-6 inhibits the replication of HCMV, HSV-1, HSV-2 and EBV. DNA polymerase-IN-6 exhibits low cytotoxicity in mammalian cells. DNA polymerase-IN-6 can be used in research related to viral infections .
Cat. No.: HY-121272
CAS No.: 98106-17-3
Synonyms: A-56619
Target:
Research Areas:
Difloxacin (A-56619) is an orally active bactericidal agent. Difloxacin inhibits bacterial DNA gyrase. Difloxacin exhibits concentration-dependent bactericidal activity. Difloxacin shows strong in vitro activity against a variety of Gram-positive and Gram-negative bacteria. Difloxacin can be used in research related to colibacillosis and Staphylococcus aureus infections .
Cat. No.: HY-N16549
CAS No.: 86631-41-6
Synonyms: 3-O-Galloylprocyanidin B3
Cat. No.: HY-106787
CAS No.: 105128-93-6
Target:
Research Areas:
HO 221 is an orally active benzoylphenylurea derivative with antitumor activity. HO 221 can inhibit the activity of mammalian DNA polymerase alpha. HO 221 can induce G1 phase arrest. HO 221 can be used for the research of cancer, such as leukemia .
Cat. No.: HY-N7066R
CAS No.: 91296-86-5
Synonyms: A-56619 hydrochloride (Standard)
Research Areas:
Difloxacin hydrochloride (Standard) (A-56619 hydrochloride (Standard)) is the analytical standard of Difloxacin (hydrochloride) (HY-N7066). This product is intended for research and analytical applications. Difloxacin hydrochloride (A-56619 hydrochloride) is an orally active bactericidal agent. Difloxacin hydrochloride inhibits bacterial DNA gyrase. Difloxacin hydrochloride exhibits concentration-dependent bactericidal activity. Difloxacin hydrochloride shows strong in vitro activity against a variety of Gram-positive and Gram-negative bacteria. Difloxacin hydrochloride can be used in research related to colibacillosis and *Staphylococcus aureus* infections .
Cat. No.: HY-186293
CAS No.: 662144-62-9
Research Areas:
3-Lauroylcatechin is a DPPH free radical scavenger. 3-Lauroylcatechin inhibits the activities of mammalian DNA polymerase α and β. 3-Lauroylcatechin can be used in studies related to colon cancer .
Cat. No.: HY-119787
CAS No.: 27267-69-2
Synonyms: Collinomycin
Cat. No.: HY-185899
CAS No.: 72052-96-1
Synonyms: 5-Aza-2'-deoxycytidine-5′-triphosphate
5-Aza-dCTP (5-Aza-2'-deoxycytidine-5′-triphosphate) is a nucleotide analog that acts as a substrate for mammalian DNA polymerase α (Km = 3.0 μM) and a weak competitive inhibitor of this enzyme (Ki = 4.3 μM). 5-Aza-dCTP inhibits DNA polymerase α via incorporation into DNA through Watson-Crick base pairing, inhibits DNA methyltransferases via incorporation into hemimethylated DNA, and induces mutations in HIV-1 via incorporation into viral DNA during synthesis. 5-Aza-dCTP reverses the inhibitory effect of dTTP on dCMP deaminase, and allosterically activates dCMP deamination to the same extent as dCTP. 5-Aza-dCTP is applicable to research related to leukemia and type 1 human immunodeficiency virus infection .
Cat. No.: HY-170547A
Target:
Research Areas:
DNA polymerase-IN-6 formic is an antiviral agent and a DNA polymerase inhibitor. DNA polymerase-IN-6 formic inhibits the replication of HCMV, HSV-1, HSV-2 and EBV. DNA polymerase-IN-6 formic exhibits low cytotoxicity in mammalian cells. DNA polymerase-IN-6 formic can be used in research related to viral infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
