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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
96 Results for "
microtubule-associated
" in MedChemExpress (MCE) Product Catalog:
Products (96)
96 Results for "microtubule-associated" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
Estramustine phosphate sodium, an estradiol analog, is an orally active antimicrotubule chemotherapy agent. Estramustine phosphate sodium depolymerises microtubules by binding to microtubule associated proteins (MAPs) and/or to tubulin. Estramustine phosphate sodium can interfere mitosis, trigger cell death and induce apoptosis, which can be used for the research of cancer like prostate cancer .
1
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Estramustine, an estradiol analog, is an orally active antimicrotubule chemotherapy agent. Estramustine depolymerises microtubules by binding to microtubule associated proteins (MAPs) and/or to tubulin. Estramustine can interfere mitosis, trigger cell death and induce apoptosis, which can be used for the research of cancer like prostate cancer .
1
1 Cited Publications
Synonyms: MASTL Kinase Inhibitor-1
MKI-1, an inhibitor of MASTL (microtubule-associated serine/threonine kinase-like) with an IC50 of 9.9 μM, exerts antitumor and radiosensitizer activities through PP2A activation in breast cancer .
1
1 Cited Publications
Cat. No.: HY-P70909
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MAP1LC3B; CDNA FLJ77661, Highly Similar To Homo Sapiens microtubule-associated Protein 1 Light Chain 3 Beta(MAP1LC3B), MRNA; microtubule associated Protein 1 Light Chain 3 Beta; microtubule-associated Protein 1 Light Chain 3 Beta, Isoform CRA_b; ATG8F; Mi
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P70589
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MAPT; Tau-Derived Paired Helical Filament Hexapeptide; Prev. MAPTL; microtubule-associated Protein Tau; Prev. DDPAC; Neurofibrillary Tangle Protein; MTBT1; Paired Helical Filament-Tau; PPP1R103; MGC138549; Tau-PHF6; FLJ31424; FTDP-17; PHF-Tau; Tau-40; Mic
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P71102
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAPT; Tau-Derived Paired Helical Filament Hexapeptide; Prev. MAPTL; microtubule-associated Protein Tau; Prev. DDPAC; Neurofibrillary Tangle Protein; MTBT1; Paired Helical Filament-Tau; PPP1R103; MGC138549; Tau-PHF6; FLJ31424; FTDP-17; PHF-Tau; Tau-40; Mic
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P701678
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MAPK3; P44-MAPK; Prev. PRKM3; Extracellular Signal-Related Kinase 1; ERK1; Mitogen-Activated Protein Kinase; P44mapk; MAP Kinase Isoform P44; P44erk1; MAP Kinase 3; ERK-1; HS44KDAP; Extracellular Signal-Regulated Kinase 1; HUMKER1A; microtubule-associated
Species:
Human
Source:
E. coli
1
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Research Areas:
MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents .
MASTL-IN-2 is an MASTL (microtubule-associated serine/threonine kinase-like) inhibitor. MASTL-IN-2 inhibits human epithelial MIA PaCa cancer cell proliferation with IC50 of 2.8 nM .
Cat. No.: HY-N3225
CAS No.: 33606-81-4
Category:
Cat. No.: HY-P9995
CAS No.: 2517973-04-3
Synonyms: JNJ-63733657
Target:
Research Areas:
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JH-VIII-157-02 is a structural analogue of alectinib, acts as an ALK inhibitor, and shows an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells.
Cat. No.: HY-P0181
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Cat. No.: HY-159653
CAS No.: 3024916-78-4
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MASTL-IN-5 (compound 11) is a MASTL (microtubule-associated serine/threonine kinase-like) inhibitor, with a Ki of 0.018 nM .
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EML4-ALK kinase inhibitor 1 is a potent orally active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM .
Cat. No.: HY-P4754
CAS No.: 565227-74-9
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Cat. No.: HY-119587
CAS No.: 139402-18-9
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Research Areas:
Alestramustine is an antineoplastic cytostatic agent that disrupts microtubule function by binding to microtubule-associated proteins and β-tubulin through its active metabolites, effectively inhibiting cell division.
Cat. No.: HY-171165
CAS No.: 1784751-83-2
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JC168 is a phenyl analog of peloruside and serves as a microtubule inhibitor, demonstrating antiproliferative and anticancer activities. JC168 promotes tubulin polymerization, thereby interfering with microtubule dynamics, and can be utilized in research related to microtubule-associated disorders .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
