1190277-80-5
1190277-80-5
Chemical Structure
MKI-1
Synonym(s): MASTL Kinase Inhibitor-1
- CAS. Nr.: 1190277-80-5
- Formula:C18H14N4O
- Molecular Weight:302.33
IUPAC Name: N-(1H-benzo[d]imidazol-2-yl)-3-(1H-pyrrol-1-yl)benzamide
InChIKey: XKDZPQAMBMLCDQ-UHFFFAOYSA-N
SMILES: O=C(NC1=NC2=CC=CC=C2N1)C3=CC=CC(N4C=CC=C4)=C3
Biological Activity: MKI-1, an inhibitor of MASTL (microtubule-associated serine/threonine kinase-like) with an IC50 of 9.9 μM, exerts antitumor and radiosensitizer activities through PP2A activation in breast cancer[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
MKI-1 | 98.13% | MKI-1, an inhibitor of MASTL (microtubule-associated serine/threonine kinase-like) with an IC50 of 9.9 μM, exerts antitumor and radiosensitizer activities through PP2A activation in breast cancer. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.67
HY-77048IRAK-4 protein kinase inhibitor 2 -
Similarity Score 0.59
HY-148315GLUT1-IN-2 -
Similarity Score 0.58
HY-157528CJ28 -
Similarity Score 0.56
HY-123984LTβR-IN-1 -
Similarity Score 0.55
HY-148766VU661 -
Similarity Score 0.55
HY-17595Mebendazole -
Similarity Score 0.55
HY-155459Tubulin polymerization-IN-57 -
Similarity Score 0.54
HY-B0413Fenbendazole -
Similarity Score 0.54
HY-149248NF-κB-IN-8 -
Explore the MedChemAI to find more analogs
