VU661
VU661, a phenazine carboxamide, is a modulator of circadian rhythms to produce a period lengthening of the circadian rhythm. VU661 is a redox-active small molecule .
For research use only. We do not sell to patients.
- CAS No.: 37648-76-3
- Formula: C19H13N3O
- Molecular Weight:299.33
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
VU661 (1, 3, 10 μM; 0-144 h) produces a period lengthening effect (7.2 h at 10 μM) in a dose-dependent manner and a minimal effect on amplitude in Bmal1-dLuc U2OS cell lines[1].
VU661 (1, 10 μM; 24 h) increases the optical redox ratio in a dose-dependent manner in cells[1].
VU661 has little to no effect on cellular ROS or hydrogen peroxide levels[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 37648-76-3
-
Molecular Weight 299.33
-
Formula C19H13N3O
-
SMILES
O=C(C1=CC2=NC3=CC=CC=C3N=C2C=C1)NC4=CC=CC=C4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz