6 Results for "

mouse HT-22 hippocampal neuronal cells

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "mouse HT-22 hippocampal neuronal cells" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N1535
CAS No.: 52617-37-5
Synonyms: Rubescensine B
Ponicidin (Rubescensine B) is an orally active RIPK1 inhibitor with a Kd value of 135 nM. Ponicidin inhibits the JAK2/STAT3 pathway to induce apoptosis, activates the PI3K/Akt pathway, upregulates SIRT1 expression, alleviates oxidative stress, suppresses inflammatory responses and necroptosis, and blocks cell cycle progression. Ponicidin induces ROS production to exert antiproliferative and antiviral effects, while also improving cognitive function and reducing plaque deposition. Ponicidin can be used in studies related to hepatocellular carcinoma, Alzheimer's disease, and gastric cancer .
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Cat. No.: HY-163280
CAS No.: 3011930-28-9
Research Areas:  

Neurological Disease

JGB-1-155 is a nicotinamide phosphoribosyltransferase (NAMPT) activator and also a reactive oxygen species (ROS) inhibitor. JGB-1-155 binds to NAMPT, thereby enhancing its catalytic activity and increasing intracellular NAD + levels. JGB-1-155 alleviates the elevation of ROS levels induced by various types of damage. JGB-1-155 can be used in research related to neurodegenerative diseases .
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Cat. No.: HY-181549
CAS No.: 3080627-61-5
PDE4-IN-32 (Compound B05) is a selective, blood-brain barrier permeable PDE4B and PDE4D inhibitor with IC50 values of 13.7 nM and 23.8 nM, respectively. PDE4-IN-32 promotes the recovery of motor and cognitive function in MCAO/R mouse models. PDE4-IN-32 reduces cerebral edema. PDE4-IN-32 can be used for the research of ischemic stroke .
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Cat. No.: HY-181178
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

(Mor-Cor)Ag(III) is a blood-brain barrier-penetrant silver(III) corrole complex that penetrates the blood-brain barrier. (Mor-Cor)Ag(III) scavenges reactive oxygen species induced by Aβ42 and disrupts Aβ42 aggregation, attenuating Aβ42-induced neuronal hyperactivity. (Mor-Cor)Ag(III) can be used for the research of Alzheimer's disease .
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Cat. No.: HY-187802
Target:  

ATP Synthase

Research Areas:  

Neurological Disease

ATPase-IN-9 is an ATP synthase inhibitor. ATPase-IN-9 binds to the F1 binding site of ATP synthase and inhibits its ATP hydrolytic activity. ATPase-IN-9 reduces intracellular ATP levels. ATPase-IN-9 can be used in research related to neurodegenerative diseases .
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Cat. No.: HY-183944
CAS No.: 214348-10-4
BN80933 is a selective neuronal nitric oxide synthase (nNOS) inhibitor with a rat Ki of 0.92 μM. BN80933 inhibits lipid peroxidation, and blocks hypoxia-induced lactate dehydrogenase elevation and delayed 8-epiprostaglandin F2α elevation. BN80933 can be used for the research of stroke, and traumatic brain injury .
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