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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
non-selective opioid antagonist
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "non-selective opioid antagonist" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P1201
CAS No.: 84211-54-1
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Cyclosomatostatin is a non-selective somatostatin receptor antagonist that blocks SSTR1-5-mediated signaling. Cyclosomatostatin decreases the ALDH + stem cell population and sphere formation without affecting cell viability, and reduces cell proliferation. Cyclosomatostatin activates opioid receptors. Cyclosomatostatin can be used for research on arthritis and colorectal cancer .
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1 Cited Publications
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Naloxone methiodide is a peripherally restricted, nonselective, and competitive opioid receptor antagonist. Naloxone methiodide does not penetrate the blood-brain barrier .
Cat. No.: HY-D1387
CAS No.: 2080300-52-1
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Naloxone fluorescein acetate is a fluorescently labeled naloxone probe used for detecting Opioid Receptor expression. Naloxone fluorescein acetate generates fluorescent signals via flow cytometry, enabling indirect evaluation of classical opioid receptor expression. Naloxone fluorescein acetate is applicable to studies related to opioid receptor expression in canine tumor cells .
Cat. No.: HY-107121
CAS No.: 676501-25-0
Synonyms: LY 2196044
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Ondelopran (LY 2196044) is a non-selective opioid receptor antagonist. Ondelopran inhibits the release of dopamine in the nucleus accumbens induced by alcohol, reduces the rewarding effect of alcohol consumption, and lowers the craving. Ondelopran can be used for alcohol use disorder (AUD) .
Cat. No.: HY-118615
CAS No.: 676495-11-7
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LY2048978 is a non-selective opioid receptor antagonist with Ki of 0.287, 0.471 and 1.05 nM for human mu, kappa and delta opioid receptors in vitro, respectively. LY2048978 can be used in the research of major depressive disorder and alcohol use disorder .
Cat. No.: HY-172149
CAS No.: 126876-64-0
Synonyms: 5'-NTII
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Naltrindole 5′-isothiocyanate (5'-NTII) is a non-selective delta opioid receptor antagonist that can antagonize the analgesic effects induced by DSLET (HY-P1332) without affecting the analgesic effects induced by DPDPE (HY-P1334) .
Cat. No.: HY-P1201A
Target:
Cyclosomatostatin TFA is a non-selective somatostatin receptor antagonist that blocks SSTR1-5-mediated signaling. Cyclosomatostatin TFA decreases the ALDH + stem cell population and sphere formation without affecting cell viability, and reduces cell proliferation. Cyclosomatostatin TFA activates opioid receptors. Cyclosomatostatin TFA can be used for research on arthritis and colorectal cancer .
Cat. No.: HY-129668
CAS No.: 75684-07-0
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Bremazocine is a potent opioid kappa receptor agonist with analgesic activity. Bremazocine induces peripheral analgesia by releasing endogenous norepinephrine. The analgesic effect of bremazocine is associated with interaction with adenosine receptors. Bremazocine produces a dose-dependent peripheral analgesia after topical application. The effect of bremazocine is affected by nonselective α(2) adrenaline receptor antagonists, suggesting that it acts through a norepinephrine pathway .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
