93302-47-7
93302-47-7
Chemical Structure
Naloxone methiodide
- CAS No.: 93302-47-7
- Formula:C20H24INO4
- Molecular Weight:469.31
IUPAC Name: (3R,4R,4aS,7aR,12bS)-3-allyl-4a,9-dihydroxy-3-methyl-7-oxo-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium iodide
InChIKey: ICONPJDAXITIPI-INJADCLWSA-N
SMILES: O[C@@]1(CCC2=O)[C@@]([C@@]2([H])OC3=C4O)(CC5)C3=C(C=C4)C[C@H]1[N@@+]5(C)CC=C.[I-]
Biological Activity: Naloxone methiodide is a peripherally restricted, nonselective, and competitive opioid receptor antagonist. Naloxone methiodide does not penetrate the blood-brain barrier[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Naloxone methiodide | 99.7% | Naloxone methiodide is a peripherally restricted, nonselective, and competitive opioid receptor antagonist. Naloxone methiodide does not penetrate the blood-brain barrier. | ||||||||||||||||||||
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References
- [1]. Basso L, et al. TRPV1 promotes opioid analgesia during inflammation. Sci Signal. 2019;12(575):eaav0711. Published 2019 Apr 2. [Content Brief]
- [2]. Basso L, et al. Endogenous control of inflammatory visceral pain by T cell-derived opioids in IL-10-deficient mice. Neurogastroenterol Motil. 2020;32(2):e13743. [Content Brief]
Keywords
